iPTMnet Report for Q8NCG7 (DAGLB)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NCG7 / DGLB_HUMAN
Protein Name Diacylglycerol lipase-beta
Gene Name Name: DAGLB
Organism Homo sapiens (Human)

PRO ID PR:Q8NCG7
DAG View
PRO Name diacylglycerol lipase-beta (human)
Definition A diacylglycerol lipase-beta that is encoded in the genome of human.
Short Label hDAGLB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NCG7 (DAGLB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S171 Phosphorylation PhosphoSitePlus
S175 Phosphorylation PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
Y318 Phosphorylation PhosphoSitePlus
S378 Phosphorylation PhosphoSitePlus
T384 Phosphorylation PhosphoSitePlus
K406 Ubiquitination PhosphoSitePlus
C465 Methylation IEDB 31844290
K509 Ubiquitination PhosphoSitePlus
S570 Phosphorylation PhosphoSitePlus   UniProt 18691976, 19690332, 20068231
Y573 Phosphorylation PhosphoSitePlus
S574 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
S576 Phosphorylation PhosphoSitePlus
S577 Phosphorylation PhosphoSitePlus
S579 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S584 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
K628 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S378 Phosphorylation HPRD 19664994
T384 Phosphorylation HPRD 19664994
S570 Phosphorylation HPRD 18691976, 20068231
S579 Phosphorylation HPRD 18669648, 20058876, 20068231
S584 Phosphorylation HPRD 18669648
S650 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
K167 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S171 R171 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
C465 Y465 Biomuta DOID:4606 / bile duct cancer [ cosmic ]