iPTMnet Report for Q8NC67 (NETO2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NC67 / NETO2_HUMAN
Protein Name Neuropilin and tolloid-like protein 2 precursor
Gene Name Name: NETO2
Synonyms:BTCL2;ORFNames:UNQ1926/PRO4401;
Organism Homo sapiens (Human)

PRO ID PR:Q8NC67
DAG View
PRO Name neuropilin and tolloid-like protein 2 (human)
Definition A neuropilin and tolloid-like protein 2 that is encoded in the genome of human.
Short Label hNETO2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NC67 (NETO2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K125 Ubiquitination PhosphoSitePlus
K200 Ubiquitination PhosphoSitePlus
K235 Ubiquitination PhosphoSitePlus
S257 Phosphorylation PhosphoSitePlus
K336 Methylation PhosphoSitePlus
T344 Phosphorylation PhosphoSitePlus
K381 Ubiquitination PhosphoSitePlus
T382 Phosphorylation PhosphoSitePlus
K386 Ubiquitination PhosphoSitePlus
Y398 Phosphorylation PhosphoSitePlus
K406 Ubiquitination PhosphoSitePlus
S409 Phosphorylation PhosphoSitePlus
S416 Phosphorylation PhosphoSitePlus
Y422 Phosphorylation PhosphoSitePlus
S455 Phosphorylation PhosphoSitePlus
S456 O-Glycosylation GlyGen 29351928
K486 Ubiquitination PhosphoSitePlus
Y509 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K386 R386 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S456 Y456 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S456 F456 Biomuta DOID:4159 / skin cancer [ cosmic ]