iPTMnet Report for Q8NC42 (RNF149)
Protein Information
| UniProt AC / UniProt ID | Q8NC42 / RN149_HUMAN |
| Protein Name | E3 ubiquitin-protein ligase RNF149 precursor |
| Gene Name | Name: RNF149 Synonyms:DNAPTP2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8NC42 |
| PRO Name | E3 ubiquitin-protein ligase RNF149 (human) |
| Definition | An E3 ubiquitin-protein ligase RNF149 that is encoded in the genome of human. |
| Short Label | hRNF149 |
| Category | organism-gene |
DAG ViewQ8NC42 (RNF149) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| N131 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| K245 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K256 | Acetylation | score1 | IEDB | 34357683 | ||
| K256 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K260 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K277 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K279 | Acetylation | score1 | IEDB | 34357683 | ||
| K279 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K288 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K310 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K315 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y319 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S354 | Methylation | score1 | IEDB | 34433824 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K256 | R256 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| K260 | R260 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| K277 | T277 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
| K310 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
