iPTMnet Report for Q8NBX0 (SCCPDH)
Protein Information
UniProt AC / UniProt ID | Q8NBX0 / SCPDL_HUMAN |
Protein Name | Saccharopine dehydrogenase-like oxidoreductase |
Gene Name | Name: SCCPDH ORFNames:CGI-49; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8NBX0 |
PRO Name | saccharopine dehydrogenase-like oxidoreductase (human) |
Definition | A saccharopine dehydrogenase-like oxidoreductase that is encoded in the genome of human. |
Short Label | hSCCPDH |
Category | organism-gene |
Q8NBX0 (SCCPDH) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K58 | Ubiquitination | score1 | PhosphoSitePlus | |||
K140 | Ubiquitination | score1 | PhosphoSitePlus | |||
K144 | Ubiquitination | score1 | PhosphoSitePlus | |||
S208 | Phosphorylation | score1 | PhosphoSitePlus | |||
K212 | Ubiquitination | score1 | PhosphoSitePlus | |||
S217 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 23186163, 20230923 | ||
K220 | Ubiquitination | score1 | PhosphoSitePlus | |||
K228 | Ubiquitination | score1 | PhosphoSitePlus | |||
K242 | Methylation | score1 | PhosphoSitePlus | |||
K242 | Ubiquitination | score1 | PhosphoSitePlus | |||
K359 | Ubiquitination | score1 | PhosphoSitePlus | |||
T362 | Phosphorylation | score1 | PhosphoSitePlus | |||
K394 | Ubiquitination | score1 | PhosphoSitePlus | |||
T400 | Phosphorylation | score1 | PhosphoSitePlus | |||
K407 | Ubiquitination | score1 | PhosphoSitePlus | |||
S425 | Phosphorylation | score1 | PhosphoSitePlus | |||
S426 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K144 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K407 | R407 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |