iPTMnet Report for Q8NBA8 (DTWD2)
Protein Information
| UniProt AC / UniProt ID | Q8NBA8 / DTWD2_HUMAN |
| Protein Name | tRNA-uridine aminocarboxypropyltransferase 2 |
| Gene Name | Name: DTWD2 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8NBA8 |
| PRO Name | tRNA-uridine aminocarboxypropyltransferase 2 (human) |
| Definition | A tRNA-uridine aminocarboxypropyltransferase 2 that is encoded in the genome of human. |
| Short Label | hDTWD2 |
| Category | organism-gene |
DAG ViewQ8NBA8 (DTWD2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| M1 | Acetylation | score1 | UniProt | 22814378 | ||
| S18 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S21 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S22 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S23 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T25 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S51 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S132 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K190 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K198 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S232 | O-Glycosylation | score1 | GlyGen | 36240223 | ||
| K271 | Methylation | score1 | PhosphoSitePlus | |||
| S295 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S18 | Y18 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S18 | F18 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| S232 | Y232 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S232 | F232 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| K271 | N271 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] |
