Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NB91 / FANCB_HUMAN
Protein Name Fanconi anemia group B protein
Gene Name Name: FANCB
Organism Homo sapiens (Human)

PRO ID PR:Q8NB91
DAG View
PRO Name Fanconi anemia group B protein (human)
Definition A Fanconi anemia group B protein that is encoded in the genome of human.
Short Label hFANCB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NB91 (FANCB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T2 Acetylation UniProt 22814378
K4 Ubiquitination PhosphoSitePlus
K39 Ubiquitination PhosphoSitePlus
K68 Ubiquitination PhosphoSitePlus
K202 Ubiquitination PhosphoSitePlus
Y205 Phosphorylation PhosphoSitePlus
K358 Ubiquitination PhosphoSitePlus
K364 Ubiquitination PhosphoSitePlus
K383 Ubiquitination PhosphoSitePlus
K415 Ubiquitination PhosphoSitePlus
K421 Ubiquitination PhosphoSitePlus
K424 Ubiquitination PhosphoSitePlus
K433 Ubiquitination PhosphoSitePlus
S456 Phosphorylation PhosphoSitePlus
S465 Phosphorylation PhosphoSitePlus
K550 Ubiquitination PhosphoSitePlus
T553 Phosphorylation PhosphoSitePlus
T555 Phosphorylation PhosphoSitePlus
K559 Ubiquitination PhosphoSitePlus
S795 Phosphorylation PhosphoSitePlus
S796 Phosphorylation PhosphoSitePlus
S803 Phosphorylation PhosphoSitePlus
T839 Phosphorylation PhosphoSitePlus
K848 Ubiquitination PhosphoSitePlus
K855 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K39 Q39 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S456 F456 Biomuta DOID:1909 / melanoma [ tcga ]
T553 P553 Biomuta DOID:263 / kidney cancer [ tcga ]
K559 N559 Biomuta DOID:363 / uterine cancer [ tcga ]
K848 N848 Biomuta DOID:363 / uterine cancer [ tcga ]