iPTMnet Report for Q8NB66 (UNC13C)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NB66 / UN13C_HUMAN
Protein Name Protein unc-13 homolog C
Gene Name Name: UNC13C
Organism Homo sapiens (Human)

PRO ID PR:Q8NB66
DAG View
PRO Name protein unc-13 homolog C (human)
Definition A protein unc-13 homolog C that is encoded in the genome of human.
Short Label hUNC13C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NB66 (UNC13C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S156 Phosphorylation PhosphoSitePlus
S159 Phosphorylation PhosphoSitePlus
S198 Phosphorylation PhosphoSitePlus
S206 Phosphorylation PhosphoSitePlus
T302 Phosphorylation PhosphoSitePlus
Y308 Phosphorylation PhosphoSitePlus
S435 Phosphorylation HPRD   PhosphoSitePlus 19413330
S458 Phosphorylation PhosphoSitePlus
S498 Phosphorylation PhosphoSitePlus
S549 Phosphorylation PhosphoSitePlus
S762 Phosphorylation PhosphoSitePlus
S764 Phosphorylation PhosphoSitePlus
S768 Phosphorylation PhosphoSitePlus
S778 Phosphorylation PhosphoSitePlus
S788 Phosphorylation PhosphoSitePlus
S793 Phosphorylation PhosphoSitePlus
S799 Phosphorylation PhosphoSitePlus
S1240 Phosphorylation PhosphoSitePlus
Y1244 Phosphorylation PhosphoSitePlus
K1294 Ubiquitination PhosphoSitePlus
K1496 Ubiquitination PhosphoSitePlus
S1534 Phosphorylation HPRD   PhosphoSitePlus 18452278
C1561 Methylation IEDB 31844290
K2100 Ubiquitination PhosphoSitePlus
K2106 Ubiquitination PhosphoSitePlus
K2113 Ubiquitination PhosphoSitePlus
C2141 Methylation IEDB 31844290
S2164 Phosphorylation PhosphoSitePlus
Y2165 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S159 N159 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S206 F206 Biomuta [ cosmic ] DOID:10283 / prostate cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
T302 A302 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S498 N498 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S549 F549 Biomuta DOID:4159 / skin cancer [ cosmic ]
S762 T762 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S764 C764 Biomuta DOID:1324 / lung cancer [ cosmic ]
S768 G768 Biomuta DOID:363 / uterine cancer [ icgc ]
S768 C768 Biomuta DOID:4159 / skin cancer [ cosmic ]
S768 N768 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S793 N793 Biomuta DOID:363 / uterine cancer [ icgc ]
S1534 C1534 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K2100 Q2100 Biomuta DOID:4159 / skin cancer [ cosmic ]
C2141 G2141 Biomuta DOID:1324 / lung cancer [ cosmic ]
C2141 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]