iPTMnet Report for Q8NAX2 (KDF1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NAX2 / KDF1_HUMAN
Protein Name Keratinocyte differentiation factor 1
Gene Name Name: KDF1
Synonyms:C1orf172;
Organism Homo sapiens (Human)

PRO ID PR:Q8NAX2
DAG View
PRO Name keratinocyte differentiation factor 1 (human)
Definition A keratinocyte differentiation factor 1 that is encoded in the genome of human.
Short Label hKDF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NAX2 (KDF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S11 Phosphorylation PhosphoSitePlus
Y30 Phosphorylation PhosphoSitePlus
S118 Phosphorylation PhosphoSitePlus
T119 Phosphorylation PhosphoSitePlus
T122 Phosphorylation PhosphoSitePlus
S137 Phosphorylation PhosphoSitePlus
S157 Phosphorylation PhosphoSitePlus
S158 Phosphorylation PhosphoSitePlus
S160 Phosphorylation PhosphoSitePlus
Y161 Phosphorylation PhosphoSitePlus
Y174 Phosphorylation PhosphoSitePlus
S179 Phosphorylation PhosphoSitePlus
S186 Phosphorylation PhosphoSitePlus
S201 Phosphorylation PhosphoSitePlus
S208 Phosphorylation PhosphoSitePlus
S209 Phosphorylation PhosphoSitePlus
S213 Phosphorylation PhosphoSitePlus
Y216 Phosphorylation PhosphoSitePlus
Y217 Phosphorylation PhosphoSitePlus
S218 Phosphorylation PhosphoSitePlus
S222 Phosphorylation PhosphoSitePlus
S305 Phosphorylation PhosphoSitePlus
T315 Phosphorylation PhosphoSitePlus
S316 Phosphorylation PhosphoSitePlus
S379 Phosphorylation PhosphoSitePlus
Y397 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S118 P118 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T119 I119 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T122 S122 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S158 G158 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
Y174 C174 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S222 L222 Biomuta DOID:1319 / brain cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
S379 L379 Biomuta DOID:1612 / breast cancer [ cosmic ]