iPTMnet Report for Q8NAV1 (PRPF38A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NAV1 / PR38A_HUMAN
Protein Name Pre-mRNA-splicing factor 38A
Gene Name Name: PRPF38A
Organism Homo sapiens (Human)

PRO ID PR:Q8NAV1
DAG View
PRO Name pre-mRNA-splicing factor 38A (human)
Definition A pre-mRNA-splicing factor 38A that is encoded in the genome of human.
Short Label hPRPF38A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NAV1 (PRPF38A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K7 Methylation PhosphoSitePlus
K7 Ubiquitination PhosphoSitePlus
S11 Phosphorylation PhosphoSitePlus   UniProt 23186163
T15 Phosphorylation PhosphoSitePlus
K23 Acetylation PhosphoSitePlus
K23 Ubiquitination PhosphoSitePlus
K66 Ubiquitination PhosphoSitePlus
K92 Sumoylation PhosphoSitePlus
K97 Acetylation PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
K118 Ubiquitination PhosphoSitePlus
K129 Ubiquitination PhosphoSitePlus
C158 Methylation IEDB 31844290
Y169 Phosphorylation PhosphoSitePlus
S182 Phosphorylation PhosphoSitePlus
S193 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18669648, 19690332, 20068231
S194 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18669648, 19690332, 20068231
S209 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18669648, 24275569, 20068231
S216 Phosphorylation PhosphoSitePlus
S226 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983
T228 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S250 Phosphorylation PhosphoSitePlus
S252 Phosphorylation PhosphoSitePlus
S260 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S262 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S268 Phosphorylation PhosphoSitePlus
S270 Phosphorylation PhosphoSitePlus
S277 Phosphorylation PhosphoSitePlus
S279 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S281 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935, 17081983
S292 Phosphorylation PhosphoSitePlus
S294 Phosphorylation PhosphoSitePlus
S296 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T68 Phosphorylation HPRD 20068231
Y169 Phosphorylation HPRD 18452278
S182 Phosphorylation HPRD 18452278
S193 Phosphorylation HPRD 19413330, 18691976, 18452278, ...19651622, 18669648, 19415658, 20068231
S194 Phosphorylation HPRD 19413330, 18691976, 18452278, ...19651622, 18669648, 19415658, 20068231
S209 Phosphorylation HPRD 18452278, 19651622, 18669648, ...18707149, 20166139, 20068231, 17924679
S226 Phosphorylation HPRD 20068231, 17924679
S260 Phosphorylation HPRD 20068231
S262 Phosphorylation HPRD 20068231
S279 Phosphorylation HPRD 20068231
S281 Phosphorylation HPRD 15302935, 20068231
S292 Phosphorylation HPRD 19651622, 20068231
S294 Phosphorylation HPRD 19651622, 20068231
S296 Phosphorylation HPRD 19651622, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T15 I15 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T228 A228 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S268 R268 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S292 C292 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]