iPTMnet Report for Q8NAT1 (POMGNT2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NAT1 / PMGT2_HUMAN
Protein Name Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2
Gene Name Name: POMGNT2
Synonyms:AGO61,C3orf39,EOGTL,GTDC2;
Organism Homo sapiens (Human)

PRO ID PR:Q8NAT1
DAG View
PRO Name protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 (human)
Definition A protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 that is encoded in the genome of human.
Short Label hPOMGNT2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NAT1 (POMGNT2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S13 Phosphorylation PhosphoSitePlus
T43 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 35289036
T65 Phosphorylation PhosphoSitePlus
T70 Phosphorylation PhosphoSitePlus
K145 Ubiquitination PhosphoSitePlus
N276 N-Glycosylation GlyGen 24190977
T379 Phosphorylation PhosphoSitePlus
Y390 Phosphorylation PhosphoSitePlus
S493 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S13 L13 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T70 S70 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
N276 S276 Biomuta DOID:1324 / lung cancer [ cosmic ]
T379 M379 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]