iPTMnet Report for Q8NAF0 (ZNF579)
Protein Information
| UniProt AC / UniProt ID | Q8NAF0 / ZN579_HUMAN |
| Protein Name | Zinc finger protein 579 |
| Gene Name | Name: ZNF579 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8NAF0 |
| PRO Name | zinc finger protein 579 (human) |
| Definition | A zinc finger protein 579 that is encoded in the genome of human. |
| Short Label | hZNF579 |
| Category | organism-gene |
Q8NAF0 (ZNF579) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S12 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R32 | Methylation | score1 | PhosphoSitePlus | |||
| R34 | Methylation | score1 | PhosphoSitePlus | |||
| S65 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S67 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
| R92 | Methylation | score2 | PhosphoSitePlus UniProt | 24129315 | ||
| S194 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 23186163, 21406692, 19664994, ... | ||
| S196 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
| K242 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S324 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S407 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
| Y454 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S483 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 23186163, 15302935, 16964243, ... | ||
| S513 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T516 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S520 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S562 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S12 | I12 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S12 | N12 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| R32 | H32 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| S513 | T513 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S513 | F513 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
DAG View