iPTMnet Report for Q8NA72 (POC5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NA72 / POC5_HUMAN
Protein Name Centrosomal protein POC5
Gene Name Name: POC5
Synonyms:C5orf37;
Organism Homo sapiens (Human)

PRO ID PR:Q8NA72
DAG View
PRO Name centrosomal protein POC5 (human)
Definition A centrosomal protein POC5 that is encoded in the genome of human.
Short Label hPOC5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NA72 (POC5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
S3 Phosphorylation PhosphoSitePlus
Y37 Phosphorylation PhosphoSitePlus
K55 Ubiquitination PhosphoSitePlus
S73 Phosphorylation PhosphoSitePlus
S78 Phosphorylation PhosphoSitePlus
T83 O-Glycosylation GlyGen 29351928
S99 Phosphorylation PhosphoSitePlus
T101 Phosphorylation PhosphoSitePlus
S104 Phosphorylation PhosphoSitePlus
S105 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 15144186
S109 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...15144186
T172 Phosphorylation PhosphoSitePlus
S176 Phosphorylation PhosphoSitePlus
S179 Phosphorylation PhosphoSitePlus
K180 Ubiquitination PhosphoSitePlus
K205 Ubiquitination PhosphoSitePlus
K228 Ubiquitination PhosphoSitePlus
Y267 Phosphorylation PhosphoSitePlus
K270 Ubiquitination PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
K334 Ubiquitination PhosphoSitePlus
K344 Ubiquitination PhosphoSitePlus
Y388 Phosphorylation PhosphoSitePlus
S414 Phosphorylation PhosphoSitePlus
S419 Phosphorylation PhosphoSitePlus
Y470 Phosphorylation PhosphoSitePlus
K481 Ubiquitination PhosphoSitePlus
S498 Phosphorylation PhosphoSitePlus
S503 Phosphorylation PhosphoSitePlus
S504 Phosphorylation PhosphoSitePlus
S505 Phosphorylation PhosphoSitePlus
S512 Phosphorylation PhosphoSitePlus
S517 Phosphorylation PhosphoSitePlus
K522 Ubiquitination PhosphoSitePlus
K538 Acetylation PhosphoSitePlus   UniProt 19608861
K538 Ubiquitination PhosphoSitePlus
S564 Phosphorylation PhosphoSitePlus   UniProt 23186163
K572 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S104 Phosphorylation HPRD 19651622, 19691289
S105 Phosphorylation HPRD 19651622, 18669648
S109 Phosphorylation HPRD 19651622, 18669648
T172 Phosphorylation HPRD 17924679
S176 Phosphorylation HPRD 17924679
S179 Phosphorylation HPRD 17924679
Site PTM Type PTM Enzyme Score Source PMID
S79 Phosphorylation HPRD 19651622, 19691289
S80 Phosphorylation HPRD 19651622, 18669648, 15144186
S84 Phosphorylation HPRD 19651622, 18669648, 15144186
T147 Phosphorylation HPRD 17924679
S151 Phosphorylation HPRD 17924679
S154 Phosphorylation HPRD 17924679


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S2 P2 Biomuta DOID:11934 / head and neck cancer [ icgc ]
K55 T55 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T83 I83 Biomuta DOID:363 / uterine cancer [ icgc ]
S84 L84 Biomuta DOID:4159 / skin cancer [ cosmic ]
S109 L109 Biomuta DOID:4159 / skin cancer [ cosmic ]
T147 K147 Biomuta DOID:363 / uterine cancer [ cosmic ]
T172 K172 Biomuta DOID:363 / uterine cancer [ cosmic ]
K270 E270 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K344 Q344 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y388 C388 Biomuta DOID:3571 / liver cancer [ cosmic ]
S503 G503 Biomuta DOID:263 / kidney cancer [ cosmic ]
S512 F512 Biomuta DOID:4159 / skin cancer [ cosmic ]
S517 L517 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S564 T564 Biomuta DOID:9256 / colorectal cancer [ cosmic ]