iPTMnet Report for Q8N9N7 (LRRC57)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N9N7 / LRC57_HUMAN
Protein Name Leucine-rich repeat-containing protein 57
Gene Name Name: LRRC57
Organism Homo sapiens (Human)

PRO ID PR:Q8N9N7
DAG View
PRO Name leucine-rich repeat-containing protein 57 (human)
Definition A leucine-rich repeat-containing protein 57 that is encoded in the genome of human.
Short Label hLRRC57
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N9N7 (LRRC57) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
G2 Myristoylation UniProt 25255805
K15 Ubiquitination PhosphoSitePlus
T16 Phosphorylation PhosphoSitePlus
K22 Ubiquitination PhosphoSitePlus
K35 Ubiquitination PhosphoSitePlus
T37 Phosphorylation HPRD   PhosphoSitePlus 20068231
S38 Phosphorylation HPRD   PhosphoSitePlus 20068231
T42 Phosphorylation HPRD   PhosphoSitePlus 20068231
S46 Phosphorylation HPRD   PhosphoSitePlus 20068231
K49 Ubiquitination PhosphoSitePlus
S52 Phosphorylation PhosphoSitePlus
K60 Ubiquitination PhosphoSitePlus
T62 Phosphorylation PhosphoSitePlus
K85 Ubiquitination PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
K140 Ubiquitination PhosphoSitePlus
C175 Methylation IEDB 31844290
K226 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T16 I16 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K35 N35 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T37 M37 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K60 N60 Biomuta DOID:10534 / stomach cancer [ cosmic ]