iPTMnet Report for Q8N9N2 (ASCC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N9N2 / ASCC1_HUMAN
Protein Name Activating signal cointegrator 1 complex subunit 1
Gene Name Name: ASCC1
ORFNames:CGI-18;
Organism Homo sapiens (Human)

PRO ID PR:Q8N9N2
DAG View
PRO Name activating signal cointegrator 1 complex subunit 1 (human)
Definition An activating signal cointegrator 1 complex subunit 1 that is encoded in the genome of human.
Short Label hASCC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N9N2 (ASCC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T25 Phosphorylation PhosphoSitePlus
Y36 Phosphorylation PhosphoSitePlus
T154 Phosphorylation PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
R284 Methylation PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
Y326 Phosphorylation PhosphoSitePlus
T327 Phosphorylation PhosphoSitePlus
K331 Ubiquitination PhosphoSitePlus
K335 Ubiquitination PhosphoSitePlus
K347 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S67 Phosphorylation PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
K82 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S67 R67 Biomuta DOID:1324 / lung cancer [ cosmic ]
S67 C67 Biomuta DOID:3571 / liver cancer [ cosmic ]
K188 E188 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R284 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K331 E331 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K335 N335 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]