iPTMnet Report for Q8N8U2 (CDYL2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N8U2 / CDYL2_HUMAN
Protein Name Chromodomain Y-like protein 2
Gene Name Name: CDYL2
Organism Homo sapiens (Human)

PRO ID PR:Q8N8U2
DAG View
PRO Name chromodomain Y-like protein 2 (human)
Definition A chromodomain Y-like protein 2 that is encoded in the genome of human.
Short Label hCDYL2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N8U2 (CDYL2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
Y25 Phosphorylation HPRD   PhosphoSitePlus 20068231
S81 Phosphorylation PhosphoSitePlus
S85 O-Glycosylation GlyGen 30379171
S85 Phosphorylation PhosphoSitePlus
K88 Ubiquitination PhosphoSitePlus
S94 Phosphorylation PhosphoSitePlus
Y120 Phosphorylation PhosphoSitePlus
S121 Phosphorylation PhosphoSitePlus
K133 Methylation PhosphoSitePlus
T139 Phosphorylation PhosphoSitePlus
T140 Phosphorylation PhosphoSitePlus
S163 Phosphorylation PhosphoSitePlus
K228 Ubiquitination PhosphoSitePlus
K234 Ubiquitination PhosphoSitePlus
S239 Phosphorylation PhosphoSitePlus
K281 Ubiquitination PhosphoSitePlus
S328 Phosphorylation PhosphoSitePlus
T329 Phosphorylation PhosphoSitePlus
K446 Ubiquitination PhosphoSitePlus
K468 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y25 H25 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S85 L85 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
S94 L94 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
K133 N133 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K234 * Biomuta DOID:4159 / skin cancer [ cosmic ]