Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N8S7 / ENAH_HUMAN
Protein Name Protein enabled homolog
Gene Name Name: ENAH
Synonyms:MENA;
Organism Homo sapiens (Human)

PRO ID PR:Q8N8S7
DAG View
PRO Name protein enabled homolog (human)
Definition A protein enabled that is encoded in the genome of human.
Short Label hENAH
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N8S7 (ENAH) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y16 Phosphorylation PhosphoSitePlus
K69 Ubiquitination PhosphoSitePlus
T116 Phosphorylation PhosphoSitePlus
T119 Phosphorylation PhosphoSitePlus
S125 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332, 17287340, 18669648, ...23186163, 20068231
S265 Phosphorylation PhosphoSitePlus
S266 Phosphorylation PhosphoSitePlus
S405 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
T410 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
S414 Phosphorylation PhosphoSitePlus
S423 Phosphorylation PhosphoSitePlus
S425 Phosphorylation PhosphoSitePlus
S426 Phosphorylation PhosphoSitePlus
S442 Phosphorylation PhosphoSitePlus
K461 Acetylation PhosphoSitePlus
K461 Ubiquitination PhosphoSitePlus
S463 Phosphorylation PhosphoSitePlus
T464 Phosphorylation PhosphoSitePlus
S477 Phosphorylation PhosphoSitePlus
T481 Phosphorylation PhosphoSitePlus
K483 Ubiquitination PhosphoSitePlus
S485 Phosphorylation PhosphoSitePlus
S486 Phosphorylation PhosphoSitePlus
T487 Phosphorylation PhosphoSitePlus
T489 Phosphorylation phospho.ELM   PhosphoSitePlus 16964243
T493 Phosphorylation PhosphoSitePlus
T500 Phosphorylation PhosphoSitePlus
T502 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 17287340
S506 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S508 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17287340, 17081983, ...20068231
S512 Phosphorylation PhosphoSitePlus
S516 Phosphorylation PhosphoSitePlus
R527 Methylation PhosphoSitePlus
S528 Phosphorylation PhosphoSitePlus
Y529 Phosphorylation PhosphoSitePlus
S531 Phosphorylation PhosphoSitePlus
K536 Ubiquitination PhosphoSitePlus
S537 Phosphorylation PhosphoSitePlus
T538 Phosphorylation phospho.ELM 18669648
S541 Phosphorylation phospho.ELM 18669648
S544 Phosphorylation PhosphoSitePlus
K559 Ubiquitination PhosphoSitePlus
K574 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S125 Phosphorylation HPRD 17525332, 17287340, 18669648, ...20068231
S405 Phosphorylation HPRD 17287340
T410 Phosphorylation HPRD 17287340
T489 Phosphorylation HPRD 16964243, 20068231, 17081983
T502 Phosphorylation HPRD 17287340
S506 Phosphorylation HPRD 18669648, 19664995, 20068231
S508 Phosphorylation HPRD 18669648, 20068231
T538 Phosphorylation HPRD 18669648
S541 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
S125 Phosphorylation HPRD   phospho.ELM 18669648, 17287340, 17525332, ...20068231
S265 Phosphorylation PhosphoSitePlus
S266 Phosphorylation PhosphoSitePlus
S405 Phosphorylation HPRD 17287340
T410 Phosphorylation HPRD 17287340
T489 Phosphorylation HPRD   PhosphoSitePlus 16964243, 20068231, 17081983
T500 Phosphorylation PhosphoSitePlus
T502 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 17287340
S506 Phosphorylation HPRD   PhosphoSitePlus 18669648, 19664995, 20068231
S508 Phosphorylation HPRD   PhosphoSitePlus 18669648, 17287340, 17081983, ...20068231
S512 Phosphorylation PhosphoSitePlus
T517 Phosphorylation HPRD 18669648
S520 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
T463 Phosphorylation PhosphoSitePlus
S469 Phosphorylation PhosphoSitePlus
S471 Phosphorylation PhosphoSitePlus
S475 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K69 T69 Biomuta DOID:363 / uterine cancer [ tcga ]
T410 A410 Biomuta DOID:363 / uterine cancer [ tcga ]
S423 Y423 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
S426 Y426 Biomuta DOID:363 / uterine cancer [ tcga ]
T487 K487 Biomuta DOID:3571 / liver cancer [ icgc ]
T493 K493 Biomuta DOID:3571 / liver cancer [ icgc ]
S512 Y512 Biomuta DOID:2394 / ovarian cancer [ tcga ] DOID:2994 / germ cell cancer [ cosmic ]
S516 F516 Biomuta DOID:1612 / breast cancer [ icgc ]
S516 Y516 Biomuta DOID:363 / uterine cancer [ tcga ]