iPTMnet Report for Q8N8N7 (PTGR2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N8N7 / PTGR2_HUMAN
Protein Name Prostaglandin reductase 2
Gene Name Name: PTGR2
Synonyms:ZADH1;
Organism Homo sapiens (Human)

PRO ID PR:Q8N8N7
DAG View
PRO Name prostaglandin reductase 2 (human)
Definition A prostaglandin reductase 2 that is encoded in the genome of human.
Short Label hPTGR2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N8N7 (PTGR2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K14 Ubiquitination PhosphoSitePlus
Y29 Phosphorylation PhosphoSitePlus
Y51 Phosphorylation PhosphoSitePlus
S270 Phosphorylation PhosphoSitePlus
Y292 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T151 Phosphorylation HPRD 20068231
S154 Phosphorylation HPRD 20068231
S181 Phosphorylation HPRD 20068231
Y292 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y29 C29 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S154 F154 Biomuta DOID:4159 / skin cancer [ cosmic ]
S270 T270 Biomuta DOID:9256 / colorectal cancer [ cosmic ]