iPTMnet Report for Q8N8L2 (ZNF491)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N8L2 / ZN491_HUMAN
Protein Name Zinc finger protein 491
Gene Name Name: ZNF491
Organism Homo sapiens (Human)

PRO ID PR:Q8N8L2
DAG View
PRO Name zinc finger protein 491 (human)
Definition A zinc finger protein 491 that is encoded in the genome of human.
Short Label hZNF491
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N8L2 (ZNF491) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T41 Phosphorylation PhosphoSitePlus
Y49 Phosphorylation PhosphoSitePlus
S51 Phosphorylation PhosphoSitePlus
K73 Methylation PhosphoSitePlus
T152 Phosphorylation PhosphoSitePlus
T154 Phosphorylation PhosphoSitePlus
T180 Phosphorylation PhosphoSitePlus
T182 Phosphorylation PhosphoSitePlus
K185 Ubiquitination PhosphoSitePlus
K190 Sumoylation PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
T208 Phosphorylation PhosphoSitePlus
T210 Phosphorylation PhosphoSitePlus
K213 Ubiquitination PhosphoSitePlus
T236 Phosphorylation PhosphoSitePlus
T238 Phosphorylation PhosphoSitePlus
K241 Ubiquitination PhosphoSitePlus
T294 Phosphorylation PhosphoSitePlus
T320 Phosphorylation PhosphoSitePlus
T322 Phosphorylation PhosphoSitePlus
T348 Phosphorylation PhosphoSitePlus
T350 Phosphorylation PhosphoSitePlus
K353 Ubiquitination PhosphoSitePlus
K358 Sumoylation PhosphoSitePlus
T406 Phosphorylation PhosphoSitePlus
K414 Ubiquitination PhosphoSitePlus
K418 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T41 I41 Biomuta DOID:5158 / pleural cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
Y49 C49 Biomuta DOID:1324 / lung cancer [ cosmic ]
S51 F51 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T154 I154 Biomuta DOID:1324 / lung cancer [ cosmic ]
K190 N190 Biomuta DOID:363 / uterine cancer [ icgc ]
K241 N241 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K241 Q241 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T322 I322 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K414 N414 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]