iPTMnet Report for Q8N884 (CGAS)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N884 / CGAS_HUMAN
Protein Name Cyclic GMP-AMP synthase
Gene Name Name: CGAS
Synonyms:C6orf150;
Organism Homo sapiens (Human)

PRO ID PR:Q8N884
DAG View
PRO Name cyclic GMP-AMP synthase (human)
Definition A protein MB21D1 that is encoded in the genome of human.
Short Label hCGAS
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N884 (CGAS) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K7 Acetylation PhosphoSitePlus   UniProt 19608861, 30799039
K7 Methylation PhosphoSitePlus
S13 Phosphorylation PhosphoSitePlus   UniProt 33542149
K21 Acetylation UniProt 32817552
S37 Phosphorylation PhosphoSitePlus   UniProt 33542149
K47 Acetylation UniProt 32817552
K50 Acetylation PhosphoSitePlus   UniProt 30799039, 32817552
K56 Acetylation UniProt 32817552
K62 Acetylation UniProt 32817552
K63 Acetylation UniProt 32817552
S64 Phosphorylation PhosphoSitePlus   UniProt 33542149
T68 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 33542149, 33273464
K82 Acetylation UniProt 32817552
K82 Methylation PhosphoSitePlus
K83 Acetylation UniProt 32817552
T91 Phosphorylation PhosphoSitePlus   UniProt 33542149, 32474700
S98 Phosphorylation UniProt 32474700
S116 Phosphorylation PhosphoSitePlus   UniProt 33542149
S120 Phosphorylation PhosphoSitePlus
C121 Methylation IEDB 31844290
R124 Methylation PhosphoSitePlus
S129 Phosphorylation PhosphoSitePlus   UniProt 33542149
S143 Phosphorylation PhosphoSitePlus   UniProt 33542149, 20068231
K164 Ubiquitination PhosphoSitePlus
K173 Ubiquitination PhosphoSitePlus   UniProt 28273161
S175 Phosphorylation PhosphoSitePlus
T181 Phosphorylation PhosphoSitePlus
K198 Acetylation PhosphoSitePlus
K198 Ubiquitination PhosphoSitePlus
S201 Phosphorylation PhosphoSitePlus
S213 Phosphorylation RLIMS-P   UniProt 33273464
Y215 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 31544964, 30356214
S221 Phosphorylation PhosphoSitePlus
K231 Sumoylation PhosphoSitePlus
Y248 Phosphorylation PhosphoSitePlus
S263 Phosphorylation PhosphoSitePlus
S278 Phosphorylation RLIMS-P 34543359
K279 Ubiquitination PhosphoSitePlus
K282 Ubiquitination PhosphoSitePlus
K285 Acetylation PhosphoSitePlus
K285 Sumoylation PhosphoSitePlus
K285 Ubiquitination PhosphoSitePlus   UniProt 27637147
K292 Acetylation PhosphoSitePlus
K292 Ubiquitination PhosphoSitePlus
T294 Phosphorylation PhosphoSitePlus
K301 Methylation PhosphoSitePlus
S305 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 26440888, 32351706, 33542149
K347 Ubiquitination PhosphoSitePlus
K355 Acetylation PhosphoSitePlus
K355 Ubiquitination PhosphoSitePlus
K362 Methylation PhosphoSitePlus
K365 Ubiquitination PhosphoSitePlus
K384 Acetylation PhosphoSitePlus   UniProt 30799039
K384 Sumoylation PhosphoSitePlus
K384 Ubiquitination PhosphoSitePlus   UniProt 28273161
K392 Acetylation PhosphoSitePlus   UniProt 30799039
K392 Ubiquitination PhosphoSitePlus
K394 Acetylation PhosphoSitePlus   UniProt 30799039
K394 Sumoylation PhosphoSitePlus
K411 Ubiquitination PhosphoSitePlus   UniProt 35503863
K414 Acetylation PhosphoSitePlus   UniProt 19608861, 30799039
K414 Ubiquitination PhosphoSitePlus   UniProt 27666593
Y415 Phosphorylation PhosphoSitePlus
K421 Ubiquitination PhosphoSitePlus
K432 Acetylation PhosphoSitePlus
K432 Ubiquitination PhosphoSitePlus
S434 Phosphorylation UniProt 32474700
S435 Phosphorylation PhosphoSitePlus   UniProt 32474700
K479 Acetylation PhosphoSitePlus
K479 Sumoylation PhosphoSitePlus
K479 Ubiquitination UniProt 27637147
K501 Ubiquitination PhosphoSitePlus
K506 Methylation UniProt 35210392
K506 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S116 Phosphorylation HPRD 20068231
S143 Phosphorylation HPRD 20068231
Y248 Phosphorylation HPRD 15592455
T294 Phosphorylation HPRD 20068231