iPTMnet Report for Q8N806 (UBR7)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N806 / UBR7_HUMAN
Protein Name Putative E3 ubiquitin-protein ligase UBR7
Gene Name Name: UBR7
Synonyms:C14orf130;
Organism Homo sapiens (Human)

PRO ID PR:Q8N806
DAG View
PRO Name putative E3 ubiquitin-protein ligase UBR7 (human)
Definition A putative E3 ubiquitin-protein ligase UBR7 that is encoded in the genome of human.
Short Label hUBR7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N806 (UBR7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S49 Phosphorylation PhosphoSitePlus
S52 Phosphorylation PhosphoSitePlus
K54 Ubiquitination PhosphoSitePlus
C75 Methylation IEDB 31844290
Y92 Phosphorylation PhosphoSitePlus
K94 Ubiquitination PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
K112 Sumoylation PhosphoSitePlus
K112 Ubiquitination PhosphoSitePlus
S190 Phosphorylation PhosphoSitePlus
K225 Sumoylation PhosphoSitePlus
K225 Ubiquitination PhosphoSitePlus
K252 Sumoylation PhosphoSitePlus
S257 Phosphorylation PhosphoSitePlus
S263 Phosphorylation PhosphoSitePlus
S264 Phosphorylation PhosphoSitePlus   UniProt 24275569
S265 Phosphorylation PhosphoSitePlus
K274 Sumoylation PhosphoSitePlus
K274 Ubiquitination PhosphoSitePlus
S277 Phosphorylation PhosphoSitePlus
K283 Sumoylation PhosphoSitePlus
K292 Ubiquitination PhosphoSitePlus
K312 Ubiquitination PhosphoSitePlus
K346 Ubiquitination PhosphoSitePlus
T351 Phosphorylation PhosphoSitePlus
S354 Phosphorylation PhosphoSitePlus   UniProt 23186163
C374 Methylation IEDB 31844290
Y376 Phosphorylation PhosphoSitePlus
K380 Ubiquitination PhosphoSitePlus
K384 Ubiquitination PhosphoSitePlus
K388 Ubiquitination PhosphoSitePlus
K398 Sumoylation PhosphoSitePlus
K398 Ubiquitination PhosphoSitePlus
K412 Ubiquitination PhosphoSitePlus
K413 Ubiquitination PhosphoSitePlus
Y422 Phosphorylation PhosphoSitePlus
Y423 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S263 C263 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K274 N274 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K292 R292 Biomuta DOID:263 / kidney cancer [ cosmic ]
K388 N388 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]