iPTMnet Report for Q8N7R7 (CCNYL1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N7R7 / CCYL1_HUMAN
Protein Name Cyclin-Y-like protein 1
Gene Name Name: CCNYL1
Organism Homo sapiens (Human)

PRO ID PR:Q8N7R7
DAG View
PRO Name cyclin-Y-like protein 1 (human)
Definition A cyclin-Y-like protein 1 that is encoded in the genome of human.
Short Label hCCNYL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N7R7 (CCNYL1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y33 Phosphorylation PhosphoSitePlus
S67 Phosphorylation PhosphoSitePlus   UniProt 24275569
S88 Phosphorylation PhosphoSitePlus
T89 Phosphorylation PhosphoSitePlus
S93 Phosphorylation PhosphoSitePlus
K94 Ubiquitination PhosphoSitePlus
S95 Phosphorylation PhosphoSitePlus
T97 Phosphorylation PhosphoSitePlus
S105 Phosphorylation PhosphoSitePlus   UniProt 21406692
S112 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 20068231
T117 Phosphorylation PhosphoSitePlus
K118 Ubiquitination PhosphoSitePlus
Y120 Phosphorylation PhosphoSitePlus
S122 Phosphorylation PhosphoSitePlus
S124 Phosphorylation PhosphoSitePlus
T125 Phosphorylation PhosphoSitePlus
K176 Ubiquitination PhosphoSitePlus
Y257 Phosphorylation PhosphoSitePlus
K316 Ubiquitination PhosphoSitePlus
K332 Ubiquitination PhosphoSitePlus
S342 Phosphorylation PhosphoSitePlus
S344 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 18669648, ...24275569, 19690332, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S35 Phosphorylation HPRD 19651622
S42 Phosphorylation HPRD 20068231
T47 Phosphorylation HPRD 20068231
S52 Phosphorylation HPRD 18669648
S272 Phosphorylation HPRD 19651622, 18578522, 19664995, ...18452278
S274 Phosphorylation HPRD 19413330, 18578522, 20058876, ...18767875, 15302935, 19664995, 19651622, 19664994, 18669648, 20166139, 19415658, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S95 C95 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y257 C257 Biomuta DOID:263 / kidney cancer [ cosmic ]
S272 Y272 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K332 R332 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S342 Y342 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]