iPTMnet Report for Q8N7J2 (AMER2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N7J2 / AMER2_HUMAN
Protein Name APC membrane recruitment protein 2
Gene Name Name: AMER2
Synonyms:FAM123A;
Organism Homo sapiens (Human)

PRO ID PR:Q8N7J2
DAG View
PRO Name APC membrane recruitment protein 2 (human)
Definition An APC membrane recruitment protein 2 that is encoded in the genome of human.
Short Label hAMER2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N7J2 (AMER2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R16 Methylation PhosphoSitePlus
S82 Phosphorylation PhosphoSitePlus
S184 Phosphorylation PhosphoSitePlus
K191 Acetylation PhosphoSitePlus
T241 Phosphorylation PhosphoSitePlus
T293 Phosphorylation PhosphoSitePlus
S409 Phosphorylation PhosphoSitePlus
T578 Phosphorylation PhosphoSitePlus
S582 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S355 Phosphorylation HPRD 15345747
S358 Phosphorylation HPRD 15345747


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R16 L16 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
R16 H16 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T241 M241 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
S358 L358 Biomuta DOID:363 / uterine cancer [ icgc ]
T578 M578 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
S582 T582 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]