iPTMnet Report for Q8N766 (EMC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N766 / EMC1_HUMAN
Protein Name ER membrane protein complex subunit 1 precursor
Gene Name Name: EMC1
Synonyms:KIAA0090;ORFNames:PSEC0263;
Organism Homo sapiens (Human)

PRO ID PR:Q8N766
DAG View
PRO Name ER membrane protein complex subunit 1 (human)
Definition An ER membrane protein complex subunit 1 that is encoded in the genome of human.
Short Label hEMC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N766 (EMC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K39 Ubiquitination PhosphoSitePlus
K41 Acetylation PhosphoSitePlus
K41 Ubiquitination PhosphoSitePlus
K52 Ubiquitination PhosphoSitePlus
K53 Ubiquitination PhosphoSitePlus
K60 Ubiquitination PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
K148 Ubiquitination PhosphoSitePlus
K201 Ubiquitination PhosphoSitePlus
C237 Methylation IEDB 31844290
T252 Phosphorylation PhosphoSitePlus
K344 Ubiquitination PhosphoSitePlus
S352 Phosphorylation PhosphoSitePlus
S355 Phosphorylation PhosphoSitePlus
S357 Phosphorylation PhosphoSitePlus
K359 Ubiquitination PhosphoSitePlus
S362 Phosphorylation PhosphoSitePlus
N370 N-Glycosylation GlyGen   UniProt 32439656
C454 Methylation IEDB 31844290
K517 Ubiquitination PhosphoSitePlus
S550 Phosphorylation PhosphoSitePlus
K565 Ubiquitination PhosphoSitePlus
Y602 Phosphorylation PhosphoSitePlus
K620 Ubiquitination PhosphoSitePlus
Y647 Phosphorylation PhosphoSitePlus
K648 Ubiquitination PhosphoSitePlus
S721 Phosphorylation PhosphoSitePlus
K734 Ubiquitination PhosphoSitePlus
T766 Phosphorylation PhosphoSitePlus
S772 Phosphorylation PhosphoSitePlus
S773 Phosphorylation PhosphoSitePlus
K776 Ubiquitination PhosphoSitePlus
N818 N-Glycosylation GlyGen   UniProt 32439656
K875 Ubiquitination PhosphoSitePlus
S899 Phosphorylation PhosphoSitePlus
N913 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 32439656, ...19159218, 24190977
Y923 Phosphorylation PhosphoSitePlus
Y938 Phosphorylation PhosphoSitePlus
K986 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N913 N-Glycosylation PRO 29741879
Y960 Phosphorylation HPRD 20068231
Y962 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K52 N52 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
N370 S370 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T766 S766 Biomuta DOID:1319 / brain cancer [ cosmic ]
S773 C773 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]