iPTMnet Report for Q8N752 (CSNK1A1L)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N752 / KC1AL_HUMAN
Protein Name Casein kinase I isoform alpha-like
Gene Name Name: CSNK1A1L
Organism Homo sapiens (Human)

PRO ID PR:Q8N752
DAG View
PRO Name casein kinase I isoform alpha-like (human)
Definition A casein kinase I isoform alpha-like that is encoded in the genome of human.
Short Label hCSNK1A1L
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N752 (CSNK1A1L) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K53 Acetylation PhosphoSitePlus
Y59 Phosphorylation PhosphoSitePlus
K62 Acetylation PhosphoSitePlus
K83 Acetylation PhosphoSitePlus
K130 Ubiquitination PhosphoSitePlus
T146 Phosphorylation PhosphoSitePlus
K152 Ubiquitination PhosphoSitePlus
K162 Ubiquitination PhosphoSitePlus
T184 Phosphorylation PhosphoSitePlus
S206 Phosphorylation PhosphoSitePlus
Y209 Phosphorylation PhosphoSitePlus
Y213 Phosphorylation PhosphoSitePlus
K240 Ubiquitination PhosphoSitePlus
T287 Phosphorylation PhosphoSitePlus
Y292 Phosphorylation PhosphoSitePlus
Y294 Phosphorylation PhosphoSitePlus
K302 Ubiquitination PhosphoSitePlus


Q8N752 (CSNK1A1L) as PTM Enzyme



Substrate Site Score Source PMID
O94916 (NFAT5) S158 PhosphoSitePlus 18411282
P35222 (CTNNB1) S45 Signor 12000790


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T146 N146 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T146 I146 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
T146 A146 Biomuta DOID:3571 / liver cancer [ cosmic ]
S206 F206 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y213 C213 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y213 H213 Biomuta DOID:363 / uterine cancer [ icgc ]
Y292 H292 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
Y294 * Biomuta DOID:1324 / lung cancer [ cosmic ]
Y294 F294 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]