iPTMnet Report for Q8N715 (CCDC185)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N715 / CC185_HUMAN
Protein Name Coiled-coil domain-containing protein 185
Gene Name Name: CCDC185
Synonyms:C1orf65;
Organism Homo sapiens (Human)

PRO ID PR:Q8N715
DAG View
PRO Name coiled-coil domain-containing protein 185 (human)
Definition A protein that is a translation product of the CCDC185 gene in human.
Short Label hCCDC185
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N715 (CCDC185) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S186 Phosphorylation PhosphoSitePlus
S190 Phosphorylation PhosphoSitePlus
S193 Phosphorylation PhosphoSitePlus
S194 Phosphorylation PhosphoSitePlus
S197 Phosphorylation PhosphoSitePlus
S324 Phosphorylation PhosphoSitePlus
S334 Phosphorylation PhosphoSitePlus
K384 Ubiquitination PhosphoSitePlus
S426 Phosphorylation PhosphoSitePlus
R515 Methylation PhosphoSitePlus
K528 Sumoylation PhosphoSitePlus
K568 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S186 F186 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S186 T186 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S190 W190 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S197 W197 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S197 L197 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
R515 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R515 G515 Biomuta DOID:263 / kidney cancer [ cosmic ]
K568 M568 Biomuta DOID:1324 / lung cancer [ cosmic ]