iPTMnet Report for Q8N6Q8 (METTL25)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N6Q8 / MET25_HUMAN
Protein Name Probable methyltransferase-like protein 25
Gene Name Name: METTL25
Synonyms:C12orf26;
Organism Homo sapiens (Human)

PRO ID PR:Q8N6Q8
DAG View
PRO Name probable methyltransferase-like protein 25 (human)
Definition A probable methyltransferase-like protein 25 that is encoded in the genome of human.
Short Label hMETTL25
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N6Q8 (METTL25) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y172 Phosphorylation PhosphoSitePlus
Y173 Phosphorylation PhosphoSitePlus
Y187 Phosphorylation PhosphoSitePlus
Y196 Phosphorylation PhosphoSitePlus
Y201 Phosphorylation PhosphoSitePlus
K255 Ubiquitination PhosphoSitePlus
S265 Phosphorylation PhosphoSitePlus
T347 Phosphorylation PhosphoSitePlus
S350 Phosphorylation PhosphoSitePlus
S367 Phosphorylation PhosphoSitePlus
C408 Methylation IEDB 31844290
K583 Acetylation PhosphoSitePlus
K583 Ubiquitination PhosphoSitePlus
K589 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y172 C172 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y187 * Biomuta DOID:10283 / prostate cancer [ cosmic ]
C408 F408 Biomuta DOID:3571 / liver cancer [ cosmic ]
K583 R583 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]