iPTMnet Report for Q8N697 (SLC15A4)
Protein Information
| UniProt AC / UniProt ID | Q8N697 / S15A4_HUMAN |
| Protein Name | Solute carrier family 15 member 4 |
| Gene Name | Name: SLC15A4 Synonyms:PHT1;ORFNames:FP12591; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8N697 |
| PRO Name | solute carrier family 15 member 4 (human) |
| Definition | A solute carrier family 15 member 4 that is encoded in the genome of human. |
| Short Label | hSLC15A4 |
| Category | organism-gene |
Q8N697 (SLC15A4) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S4 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S109 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y113 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T128 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S135 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N140 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| C232 | Methylation | score1 | IEDB | 31844290 | ||
| K272 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S291 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K292 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S294 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S298 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K300 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K311 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K316 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y477 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S478 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S504 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C530 | Methylation | score1 | IEDB | 31844290 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| C232 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S291 | F291 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| S298 | L298 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K300 | R300 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| Y477 | H477 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S478 | L478 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] |
DAG View