iPTMnet Report for Q8N680 (ZBTB2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N680 / ZBTB2_HUMAN
Protein Name Zinc finger and BTB domain-containing protein 2
Gene Name Name: ZBTB2
Synonyms:KIAA1483,ZNF437;
Organism Homo sapiens (Human)

PRO ID PR:Q8N680
DAG View
PRO Name zinc finger and BTB domain-containing protein 2 (human)
Definition A zinc finger and BTB domain-containing protein 2 that is encoded in the genome of human.
Short Label hZBTB2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N680 (ZBTB2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S115 Phosphorylation Q13315 (ATM) PhosphoSitePlus 17478428
S167 Phosphorylation PhosphoSitePlus
S175 Phosphorylation PhosphoSitePlus
S178 Phosphorylation PhosphoSitePlus
T193 Phosphorylation PhosphoSitePlus
S203 Phosphorylation PhosphoSitePlus
S341 Phosphorylation PhosphoSitePlus   UniProt 24275569
K362 Sumoylation PhosphoSitePlus
K388 Sumoylation PhosphoSitePlus
K391 Methylation PhosphoSitePlus
S398 Phosphorylation PhosphoSitePlus
S414 Phosphorylation PhosphoSitePlus
S435 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17525332
T456 Phosphorylation PhosphoSitePlus
S458 Phosphorylation PhosphoSitePlus
T459 Phosphorylation PhosphoSitePlus
S483 Phosphorylation PhosphoSitePlus
S488 Phosphorylation PhosphoSitePlus
S491 Phosphorylation PhosphoSitePlus
T494 Phosphorylation PhosphoSitePlus
K505 Sumoylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S115 I115 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S115 R115 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K362 R362 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S398 G398 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S414 R414 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S458 C458 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T494 M494 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]