iPTMnet Report for Q8N653 (LZTR1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N653 / LZTR1_HUMAN
Protein Name Leucine-zipper-like transcriptional regulator 1
Gene Name Name: LZTR1
Synonyms:TCFL2;
Organism Homo sapiens (Human)

PRO ID PR:Q8N653
DAG View
PRO Name leucine-zipper-like transcriptional regulator 1 (human)
Definition A leucine-zipper-like transcriptional regulator 1 that is encoded in the genome of human.
Short Label hLZTR1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N653 (LZTR1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
K101 Ubiquitination PhosphoSitePlus
T111 Phosphorylation PhosphoSitePlus
T113 Phosphorylation PhosphoSitePlus
Y119 Phosphorylation PhosphoSitePlus
Y141 Phosphorylation PhosphoSitePlus
K149 Ubiquitination PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
S244 Phosphorylation PhosphoSitePlus
S247 Phosphorylation PhosphoSitePlus
K261 Ubiquitination PhosphoSitePlus
T270 Phosphorylation PhosphoSitePlus
R275 Methylation PhosphoSitePlus
C342 Methylation IEDB 31844290
Y352 Phosphorylation PhosphoSitePlus
K375 Ubiquitination PhosphoSitePlus
K426 Ubiquitination PhosphoSitePlus
K484 Ubiquitination PhosphoSitePlus
K615 Ubiquitination PhosphoSitePlus
K682 Ubiquitination PhosphoSitePlus
Y726 Phosphorylation PhosphoSitePlus
C833 Methylation IEDB 31844290


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T113 I113 Biomuta DOID:4159 / skin cancer [ cosmic ]
S244 C244 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y352 H352 Biomuta DOID:363 / uterine cancer [ cosmic ]
K375 N375 Biomuta DOID:9256 / colorectal cancer [ cosmic ]