iPTMnet Report for Q8N608 (DPP10)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N608 / DPP10_HUMAN
Protein Name Inactive dipeptidyl peptidase 10
Gene Name Name: DPP10
Synonyms:DPRP3,KIAA1492;
Organism Homo sapiens (Human)

PRO ID PR:Q8N608
DAG View
PRO Name inactive dipeptidyl peptidase 10 (human)
Definition An inactive dipeptidyl peptidase 10 that is encoded in the genome of human.
Short Label hDPP10
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N608 (DPP10) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N63 N-Glycosylation GlyGen 29671580
N90 N-Glycosylation GlyGen   UniProt 22387313
N111 N-Glycosylation GlyGen   UniProt 22387313
N119 N-Glycosylation GlyGen   UniProt 22387313
S133 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y138 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
Y143 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
N257 N-Glycosylation GlyGen   UniProt 22387313
T270 Phosphorylation PhosphoSitePlus
Y274 Phosphorylation PhosphoSitePlus
Y280 Phosphorylation PhosphoSitePlus
Y282 Phosphorylation PhosphoSitePlus
S316 Phosphorylation PhosphoSitePlus
Y319 Phosphorylation PhosphoSitePlus
Y320 Phosphorylation PhosphoSitePlus
S328 Phosphorylation PhosphoSitePlus
N342 N-Glycosylation GlyGen   UniProt 22387313
Y512 Phosphorylation PhosphoSitePlus
K669 Acetylation PhosphoSitePlus
K729 Acetylation PhosphoSitePlus
N748 N-Glycosylation GlyGen   UniProt 22387313
Y754 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N63 N-Glycosylation PRO 29671580
S133 Phosphorylation HPRD 18669648
Y138 Phosphorylation HPRD 18669648
Y143 Phosphorylation HPRD 18669648
S467 Phosphorylation HPRD 17081983
S481 Phosphorylation HPRD 17081983
S483 Phosphorylation HPRD 17081983
Site PTM Type PTM Enzyme Score Source PMID
S126 Phosphorylation HPRD 18669648
Y131 Phosphorylation HPRD 18669648
Y136 Phosphorylation HPRD 18669648
S460 Phosphorylation HPRD 17081983
S474 Phosphorylation HPRD 17081983
S476 Phosphorylation HPRD 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N90 D90 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S126 L126 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ]
S133 L133 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ]
T270 N270 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y319 C319 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
Y319 S319 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y320 H320 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S328 N328 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S328 T328 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S460 L460 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S467 L467 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S476 C476 Biomuta DOID:3571 / liver cancer [ cosmic ]
S476 N476 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S483 N483 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S483 C483 Biomuta DOID:3571 / liver cancer [ cosmic ]
K729 T729 Biomuta DOID:1324 / lung cancer [ icgc ]
K729 N729 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]