iPTMnet Report for Q8N5Z0 (AADAT)
Protein Information
| UniProt AC / UniProt ID | Q8N5Z0 / AADAT_HUMAN |
| Protein Name | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial precursor |
| Gene Name | Name: AADAT Synonyms:KAT2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8N5Z0 |
| PRO Name | kynurenine/alpha-aminoadipate aminotransferase, mitochondrial (human) |
| Definition | A kynurenine/alpha-aminoadipate aminotransferase, mitochondrial that is encoded in the genome of human. |
| Short Label | hAADAT |
| Category | organism-gene |
DAG ViewQ8N5Z0 (AADAT) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K31 | Acetylation | score1 | PhosphoSitePlus | |||
| S32 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S35 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K49 | Acetylation | score1 | PhosphoSitePlus | |||
| K69 | Acetylation | score1 | PhosphoSitePlus | |||
| S176 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K367 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S32 | L32 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| S35 | F35 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S176 | A176 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S176 | F176 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |
