iPTMnet Report for Q8N5Y2 (MSL3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N5Y2 / MS3L1_HUMAN
Protein Name Male-specific lethal 3 homolog
Gene Name Name: MSL3
Synonyms:MSL3L1;
Organism Homo sapiens (Human)

PRO ID PR:Q8N5Y2
DAG View
PRO Name male-specific lethal 3 homolog (human)
Definition A male-specific lethal 3 that is encoded in the genome of human.
Short Label hMSL3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N5Y2 (MSL3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K85 Acetylation PhosphoSitePlus
S144 Phosphorylation PhosphoSitePlus
S147 Phosphorylation PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
S224 Phosphorylation PhosphoSitePlus
K283 Ubiquitination PhosphoSitePlus
K289 Ubiquitination PhosphoSitePlus
K295 Ubiquitination PhosphoSitePlus
S311 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
S318 Phosphorylation PhosphoSitePlus
T319 Phosphorylation PhosphoSitePlus
T323 Phosphorylation PhosphoSitePlus
S325 Phosphorylation PhosphoSitePlus
T334 Phosphorylation PhosphoSitePlus
S347 Phosphorylation PhosphoSitePlus
S365 Phosphorylation PhosphoSitePlus
S367 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
K383 Acetylation PhosphoSitePlus
K383 Ubiquitination PhosphoSitePlus
K390 Ubiquitination PhosphoSitePlus
T392 Phosphorylation PhosphoSitePlus
S396 Phosphorylation PhosphoSitePlus
S398 Phosphorylation PhosphoSitePlus
S399 Phosphorylation PhosphoSitePlus
S400 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 21406692, 23186163, ...18669648
T405 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S407 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S411 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
Site PTM Type PTM Enzyme Score Source PMID
S367 Phosphorylation HPRD 18669648, 19007248, 20068231
S398 Phosphorylation HPRD 20058876
S400 Phosphorylation HPRD 19413330, 18669648, 15302935, ...20068231
T405 Phosphorylation HPRD 18669648, 20068231
S407 Phosphorylation HPRD 18669648
S411 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
T17 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S201 Phosphorylation HPRD 18669648, 19007248, 20068231
S232 Phosphorylation HPRD 20058876
S233 Phosphorylation HPRD 15302935
S234 Phosphorylation HPRD 19413330, 18669648, 15302935, ...20068231
T239 Phosphorylation HPRD 18669648, 20068231
S241 Phosphorylation HPRD 18669648
S245 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
S367 Phosphorylation HPRD 18669648, 19007248, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K289 T289 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K289 N289 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S318 F318 Biomuta DOID:4159 / skin cancer [ cosmic ]
S318 P318 Biomuta DOID:363 / uterine cancer [ icgc ]
T319 M319 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ]
S347 F347 Biomuta DOID:1612 / breast cancer [ cosmic ]
S365 I365 Biomuta DOID:1319 / brain cancer [ icgc ]
S365 N365 Biomuta DOID:1324 / lung cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
T392 I392 Biomuta DOID:1319 / brain cancer [ cosmic ]
S398 L398 Biomuta DOID:4159 / skin cancer [ cosmic ]
S398 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S399 F399 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T405 S405 Biomuta DOID:1324 / lung cancer [ cosmic ]