Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N5U6 / RNF10_HUMAN
Protein Name E3 ubiquitin-protein ligase RNF10
Gene Name Name: RNF10
Synonyms:KIAA0262;
Organism Homo sapiens (Human)

PRO ID PR:Q8N5U6
DAG View
PRO Name RING finger protein 10 (human)
Definition A RING finger protein 10 that is encoded in the genome of human.
Short Label hRNF10
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N5U6 (RNF10) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S5 Phosphorylation PhosphoSitePlus   UniProt 23186163
S39 Phosphorylation PhosphoSitePlus
S41 Phosphorylation PhosphoSitePlus
S70 Phosphorylation PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
S76 Phosphorylation PhosphoSitePlus
S103 Phosphorylation PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
S110 Phosphorylation PhosphoSitePlus   UniProt 23186163
S128 Phosphorylation PhosphoSitePlus   UniProt 23186163
S133 Phosphorylation PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
K137 Ubiquitination PhosphoSitePlus
S164 Phosphorylation PhosphoSitePlus
S277 Phosphorylation PhosphoSitePlus
T293 Phosphorylation PhosphoSitePlus
K301 Acetylation PhosphoSitePlus
K309 Acetylation PhosphoSitePlus
K311 Ubiquitination PhosphoSitePlus
K331 Ubiquitination PhosphoSitePlus
K337 Ubiquitination PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus
K360 Ubiquitination PhosphoSitePlus
K376 Ubiquitination PhosphoSitePlus
T393 Phosphorylation PhosphoSitePlus
K494 Ubiquitination PhosphoSitePlus
S502 Phosphorylation PhosphoSitePlus
S503 Phosphorylation PhosphoSitePlus
S670 Phosphorylation PhosphoSitePlus
K722 Acetylation PhosphoSitePlus
K728 Ubiquitination PhosphoSitePlus
S786 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S39 P39 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S128 N128 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T293 M293 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K301 N301 Biomuta DOID:363 / uterine cancer [ cosmic ]
K301 I301 Biomuta DOID:363 / uterine cancer [ cosmic ]
T393 I393 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S786 F786 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]