iPTMnet Report for Q8N5T2 (TBC1D19)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N5T2 / TBC19_HUMAN
Protein Name TBC1 domain family member 19
Gene Name Name: TBC1D19
Organism Homo sapiens (Human)

PRO ID PR:Q8N5T2
DAG View
PRO Name TBC1 domain family member 19 (human)
Definition A TBC1 domain family member 19 that is encoded in the genome of human.
Short Label hTBC1D19
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N5T2 (TBC1D19) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K18 Acetylation PhosphoSitePlus
K20 Acetylation PhosphoSitePlus
Y25 Phosphorylation phospho.ELM   PhosphoSitePlus 15592455
S45 Phosphorylation PhosphoSitePlus
K47 Ubiquitination PhosphoSitePlus
Y68 Phosphorylation PhosphoSitePlus
Y93 Phosphorylation PhosphoSitePlus
K130 Ubiquitination PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
K234 Ubiquitination PhosphoSitePlus
T282 Phosphorylation IEDB 35494241
T327 Phosphorylation PhosphoSitePlus
S328 Phosphorylation PhosphoSitePlus
S339 Phosphorylation PhosphoSitePlus
Y354 Phosphorylation PhosphoSitePlus
Y358 Phosphorylation PhosphoSitePlus
Y387 Phosphorylation PhosphoSitePlus
S509 Phosphorylation PhosphoSitePlus
T510 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K18 Q18 Biomuta DOID:9256 / colorectal cancer [ icgc ]
Y25 F25 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y93 C93 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:1324 / lung cancer [ cosmic ]
K130 N130 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
K234 I234 Biomuta DOID:3571 / liver cancer [ cosmic ]
T327 K327 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T327 I327 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ]
S339 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S339 L339 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
Y358 F358 Biomuta DOID:1324 / lung cancer [ cosmic ]