iPTMnet Report for Q8N5P1 (ZC3H8)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N5P1 / ZC3H8_HUMAN
Protein Name Zinc finger CCCH domain-containing protein 8
Gene Name Name: ZC3H8
Synonyms:ZC3HDC8;
Organism Homo sapiens (Human)

PRO ID PR:Q8N5P1
DAG View
PRO Name zinc finger CCCH domain-containing protein 8 (human)
Definition A zinc finger CCCH domain-containing protein 8 that is encoded in the genome of human.
Short Label hZC3H8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N5P1 (ZC3H8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S22 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 18452278
T32 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332
K43 Sumoylation PhosphoSitePlus
S56 Phosphorylation HPRD   PhosphoSitePlus 20068231
S59 Phosphorylation HPRD   IEDB   PhosphoSitePlus   UniProt 23186163, 32387766, 20068231
K61 Ubiquitination PhosphoSitePlus
S62 Phosphorylation HPRD 20068231
S63 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 20068231
S68 Phosphorylation PhosphoSitePlus
S70 Phosphorylation PhosphoSitePlus
K71 Methylation PhosphoSitePlus
Y73 Phosphorylation PhosphoSitePlus
Y76 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S77 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 17525332, 18077418, ...18669648
S83 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17525332, 18077418
S86 Phosphorylation PhosphoSitePlus
T121 Phosphorylation PhosphoSitePlus
K140 Acetylation PhosphoSitePlus
K147 Acetylation PhosphoSitePlus
S165 Phosphorylation PhosphoSitePlus
K175 Ubiquitination PhosphoSitePlus
Y199 Phosphorylation HPRD   PhosphoSitePlus 20068231
Y229 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S22 F22 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T32 I32 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S56 P56 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S63 L63 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
K147 E147 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y199 S199 Biomuta DOID:363 / uterine cancer [ icgc ]
Y229 * Biomuta DOID:1324 / lung cancer [ cosmic ]