Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N5K1 / CISD2_HUMAN
Protein Name CDGSH iron-sulfur domain-containing protein 2
Gene Name Name: CISD2
Synonyms:CDGSH2,ERIS,ZCD2;
Organism Homo sapiens (Human)

PRO ID PR:Q8N5K1
DAG View
PRO Name CDGSH iron-sulfur domain-containing protein 2 (human)
Definition A CDGSH iron-sulfur domain-containing protein 2 that is encoded in the genome of human.
Short Label hCISD2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N5K1 (CISD2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K19 Ubiquitination PhosphoSitePlus
S36 Phosphorylation HPRD   PhosphoSitePlus 20068231
K67 Ubiquitination PhosphoSitePlus
S69 Phosphorylation PhosphoSitePlus
K74 Ubiquitination PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus
K95 Ubiquitination PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
T106 Phosphorylation PhosphoSitePlus
K131 Methylation PhosphoSitePlus
K132 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T106 M106 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]