iPTMnet Report for Q8N5I9 (NOPCHAP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N5I9 / NOPC1_HUMAN
Protein Name NOP protein chaperone 1
Gene Name Name: NOPCHAP1
Synonyms:C12orf45;
Organism Homo sapiens (Human)

PRO ID PR:Q8N5I9
DAG View
PRO Name NOP protein chaperone 1 (human)
Definition A NOP protein chaperone 1 that is encoded in the genome of human.
Short Label hNOPCHAP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N5I9 (NOPCHAP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K6 Acetylation PhosphoSitePlus
S10 Phosphorylation PhosphoSitePlus
S14 Phosphorylation HPRD   PhosphoSitePlus 19664995
S15 Phosphorylation HPRD   PhosphoSitePlus 19664995
T17 Phosphorylation PhosphoSitePlus
S20 Phosphorylation HPRD 20068231
K27 Ubiquitination PhosphoSitePlus
S34 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
R37 Methylation PhosphoSitePlus
S48 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231
K51 Ubiquitination PhosphoSitePlus
K54 Ubiquitination PhosphoSitePlus
S56 Phosphorylation PhosphoSitePlus
S66 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231, 18220336
K88 Ubiquitination PhosphoSitePlus
S134 Phosphorylation PhosphoSitePlus
S135 Phosphorylation PhosphoSitePlus
K162 Ubiquitination PhosphoSitePlus
K172 Ubiquitination PhosphoSitePlus
S178 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 23186163, ...19664994, 19664995, 18452278, 19651622, 18669648, 19690332, 20068231
S181 Phosphorylation HPRD   PhosphoSitePlus 19413330


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S10 N10 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T17 A17 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S34 G34 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S66 G66 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K162 E162 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K162 N162 Biomuta DOID:1324 / lung cancer [ cosmic ]
S181 R181 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]