iPTMnet Report for Q8N5H7 (SH2D3C)
Protein Information
UniProt AC / UniProt ID | Q8N5H7 / SH2D3_HUMAN |
Protein Name | SH2 domain-containing protein 3C |
Gene Name | Name: SH2D3C Synonyms:NSP3;ORFNames:UNQ272/PRO309/PRO34088; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8N5H7 |
PRO Name | SH2 domain-containing protein 3C (human) |
Definition | An SH2 domain-containing protein 3C that is encoded in the genome of human. |
Short Label | hSH2D3C |
Category | organism-gene |
Q8N5H7 (SH2D3C) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K7 | Acetylation | score1 | PhosphoSitePlus | |||
S22 | Phosphorylation | score1 | PhosphoSitePlus | |||
S24 | Phosphorylation | score1 | PhosphoSitePlus | |||
S63 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y74 | Phosphorylation | score1 | PhosphoSitePlus | |||
S84 | Phosphorylation | score1 | PhosphoSitePlus | |||
S181 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y183 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18083107 | ||
K190 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y191 | Phosphorylation | score1 | PhosphoSitePlus | |||
S196 | Phosphorylation | score1 | PhosphoSitePlus | |||
K199 | Ubiquitination | score1 | PhosphoSitePlus | |||
K202 | Ubiquitination | score1 | PhosphoSitePlus | |||
S212 | Phosphorylation | score1 | PhosphoSitePlus | |||
T213 | Phosphorylation | score1 | PhosphoSitePlus | |||
S277 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y278 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y316 | Phosphorylation | score1 | PhosphoSitePlus | |||
K340 | Ubiquitination | score1 | PhosphoSitePlus | |||
S343 | Phosphorylation | score1 | PhosphoSitePlus | |||
S346 | Phosphorylation | score1 | PhosphoSitePlus | |||
S348 | Phosphorylation | score1 | PhosphoSitePlus | |||
S359 | Phosphorylation | score1 | PhosphoSitePlus | |||
T361 | Phosphorylation | score1 | PhosphoSitePlus | |||
S416 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y419 | Phosphorylation | score1 | PhosphoSitePlus | |||
T421 | Phosphorylation | score1 | PhosphoSitePlus | |||
T423 | Phosphorylation | score1 | PhosphoSitePlus | |||
T435 | Phosphorylation | score1 | PhosphoSitePlus | |||
S440 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S446 | Phosphorylation | score1 | PhosphoSitePlus | |||
S447 | Phosphorylation | score1 | PhosphoSitePlus | |||
S463 | Phosphorylation | score1 | PhosphoSitePlus | |||
S472 | Phosphorylation | score1 | PhosphoSitePlus | |||
T474 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y487 | Phosphorylation | score1 | PhosphoSitePlus | |||
S488 | Phosphorylation | score1 | PhosphoSitePlus | |||
S492 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y495 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 16497976 | ||
K526 | Ubiquitination | score1 | PhosphoSitePlus | |||
K579 | Ubiquitination | score1 | PhosphoSitePlus | |||
K609 | Ubiquitination | score1 | PhosphoSitePlus | |||
K727 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y793 | Phosphorylation | score1 | PhosphoSitePlus | |||
S826 | Phosphorylation | score1 | PhosphoSitePlus | |||
K842 | Ubiquitination | score1 | PhosphoSitePlus | |||
K850 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S212 | Phosphorylation | score0 | HPRD | 18491316 | ||
T213 | Phosphorylation | score0 | HPRD | 18491316 | ||
Y487 | Phosphorylation | score0 | HPRD | 19901323, 16497976 | ||
Y495 | Phosphorylation | score0 | HPRD | 19901323, 16497976 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y26 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18083107 | ||
S55 | Phosphorylation | score0 | HPRD | 18491316 | ||
T56 | Phosphorylation | score0 | HPRD | 18491316 | ||
S283 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y330 | Phosphorylation | score0 | HPRD | 19901323, 16497976 | ||
Y338 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 19901323, 16497976 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S22 | G22 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] | |
S63 | I63 | Biomuta | DOID:1793 / pancreatic cancer [ tcga ] | |
S84 | G84 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S181 | G181 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
S196 | L196 | Biomuta | DOID:4362 / cervical cancer [ tcga ] | |
K202 | T202 | Biomuta | DOID:363 / uterine cancer [ tcga ] | |
Y278 | C278 | Biomuta | DOID:263 / kidney cancer [ tcga ] | |
S416 | F416 | Biomuta | DOID:4362 / cervical cancer [ tcga ] | |
T423 | A423 | Biomuta | DOID:3963 / thyroid carcinoma [ cosmic, icgc ] | |
S440 | F440 | Biomuta | DOID:3070 / malignant glioma [ cosmic ] | |
S463 | * | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
Y487 | * | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
Y793 | S793 | Biomuta | DOID:3963 / thyroid carcinoma [ cosmic ] |