iPTMnet Report for Q8N5D0 (WDTC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N5D0 / WDTC1_HUMAN
Protein Name WD and tetratricopeptide repeats protein 1
Gene Name Name: WDTC1
Synonyms:KIAA1037;
Organism Homo sapiens (Human)

PRO ID PR:Q8N5D0
DAG View
PRO Name WD and tetratricopeptide repeats protein 1 (human)
Definition A WD and tetratricopeptide repeats protein 1 that is encoded in the genome of human.
Short Label hWDTC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N5D0 (WDTC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y27 Phosphorylation PhosphoSitePlus
T30 Phosphorylation PhosphoSitePlus
K80 Ubiquitination PhosphoSitePlus
Y212 Phosphorylation PhosphoSitePlus
S227 Phosphorylation PhosphoSitePlus
S353 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y399 Phosphorylation PhosphoSitePlus
Y406 Phosphorylation PhosphoSitePlus
K410 Ubiquitination PhosphoSitePlus
Y416 Phosphorylation PhosphoSitePlus
K424 Acetylation PhosphoSitePlus
K424 Ubiquitination PhosphoSitePlus
S427 Phosphorylation PhosphoSitePlus
K460 Ubiquitination PhosphoSitePlus
K462 Ubiquitination PhosphoSitePlus
K486 Ubiquitination PhosphoSitePlus
K493 Ubiquitination PhosphoSitePlus
K509 Ubiquitination PhosphoSitePlus
S511 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332, 20068231
S513 Phosphorylation PhosphoSitePlus
S662 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S510 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K80 Q80 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S427 F427 Biomuta DOID:4159 / skin cancer [ cosmic ]
K462 N462 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S510 F510 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S511 F511 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]