iPTMnet Report for Q8N5C7 (DTWD1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N5C7 / DTWD1_HUMAN
Protein Name tRNA-uridine aminocarboxypropyltransferase 1
Gene Name Name: DTWD1
ORFNames:MDS009;
Organism Homo sapiens (Human)

PRO ID PR:Q8N5C7
DAG View
PRO Name tRNA-uridine aminocarboxypropyltransferase 1 (human)
Definition A tRNA-uridine aminocarboxypropyltransferase 1 that is encoded in the genome of human.
Short Label hDTWD1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N5C7 (DTWD1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 22814378
K10 Methylation PhosphoSitePlus
K10 Sumoylation PhosphoSitePlus
K18 Acetylation PhosphoSitePlus
K18 Ubiquitination PhosphoSitePlus
K97 Acetylation PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
K105 Acetylation PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
K177 Ubiquitination PhosphoSitePlus
T181 Phosphorylation PhosphoSitePlus
S192 Phosphorylation PhosphoSitePlus
K193 Ubiquitination PhosphoSitePlus
K269 Sumoylation PhosphoSitePlus
Y270 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K18 T18 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
K105 R105 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y270 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]