iPTMnet Report for Q8N5C6 (SRBD1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N5C6 / SRBD1_HUMAN
Protein Name S1 RNA-binding domain-containing protein 1
Gene Name Name: SRBD1
Organism Homo sapiens (Human)

PRO ID PR:Q8N5C6
DAG View
PRO Name S1 RNA-binding domain-containing protein 1 (human)
Definition An S1 RNA-binding domain-containing protein 1 that is encoded in the genome of human.
Short Label hSRBD1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N5C6 (SRBD1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S28 Phosphorylation PhosphoSitePlus
S29 Phosphorylation PhosphoSitePlus
S31 Phosphorylation PhosphoSitePlus
S59 O-Glycosylation GlyGen 30379171
S89 Phosphorylation PhosphoSitePlus
S90 Phosphorylation PhosphoSitePlus
T107 Phosphorylation PhosphoSitePlus
K134 Sumoylation PhosphoSitePlus
K166 Sumoylation PhosphoSitePlus
S179 Phosphorylation PhosphoSitePlus
K185 Sumoylation PhosphoSitePlus
S319 O-Glycosylation GlyGen 30379171
K381 Ubiquitination PhosphoSitePlus
S406 Phosphorylation PhosphoSitePlus
S407 Phosphorylation PhosphoSitePlus
K494 Ubiquitination PhosphoSitePlus
S511 Phosphorylation PhosphoSitePlus
K547 Ubiquitination PhosphoSitePlus
K757 Acetylation PhosphoSitePlus
S861 Phosphorylation PhosphoSitePlus   UniProt 23186163
K955 Sumoylation PhosphoSitePlus
S964 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
R986 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S28 Phosphorylation HPRD 17081983
S29 Phosphorylation HPRD 17081983
S31 Phosphorylation HPRD 17081983
S861 Phosphorylation HPRD 20068231
S964 Phosphorylation HPRD 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S28 L28 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ]
T107 S107 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
K134 N134 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S861 P861 Biomuta DOID:363 / uterine cancer [ icgc ]
R986 W986 Biomuta DOID:3571 / liver cancer [ cosmic ]