iPTMnet Report for Q8N5A5 (ZGPAT)
Protein Information
| UniProt AC / UniProt ID | Q8N5A5 / ZGPAT_HUMAN |
| Protein Name | Zinc finger CCCH-type with G patch domain-containing protein |
| Gene Name | Name: ZGPAT Synonyms:GPATC6,GPATCH6,KIAA1847,ZC3H9,ZC3HDC9,ZIP; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8N5A5 |
| PRO Name | zinc finger CCCH-type with G patch domain-containing protein (human) |
| Definition | A zinc finger CCCH-type with G patch domain-containing protein that is encoded in the genome of human. |
| Short Label | hZGPAT |
| Category | organism-gene |
Q8N5A5 (ZGPAT) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| M1 | Acetylation | score1 | UniProt | 22814378 | ||
| Y13 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y79 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S101 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y169 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K178 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K187 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K227 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S252 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T274 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S276 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S278 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S280 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| T283 | Phosphorylation | score1 | phospho.ELM | 18669648 | ||
| S338 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K343 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R370 | Methylation | score1 | PhosphoSitePlus | |||
| K372 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S373 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K383 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R401 | Methylation | score1 | PhosphoSitePlus | |||
| R404 | Methylation | score1 | PhosphoSitePlus | |||
| K421 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K442 | Methylation | score1 | PhosphoSitePlus | |||
| S475 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K497 | Ubiquitination | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T274 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S276 | Phosphorylation | score0 | HPRD | 18669648, 17081983, 20068231 | ||
| S278 | Phosphorylation | score0 | HPRD | 18669648, 17081983, 20068231 | ||
| S280 | Phosphorylation | score0 | HPRD | 18669648, 17081983, 20068231 | ||
| T283 | Phosphorylation | score0 | HPRD | 18669648 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T274 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S276 | Phosphorylation | score0 | HPRD | 18669648, 17081983, 20068231 | ||
| S278 | Phosphorylation | score0 | HPRD | 18669648, 17081983, 20068231 | ||
| S280 | Phosphorylation | score0 | HPRD | 18669648, 17081983, 20068231 | ||
| T283 | Phosphorylation | score0 | HPRD | 18669648 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y13 | C13 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| Y79 | * | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ] | |
| K187 | E187 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| K227 | * | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| S252 | L252 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| T283 | M283 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| R370 | Q370 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| S373 | L373 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] |
DAG View