Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N4S9 / MALD2_HUMAN
Protein Name MARVEL domain-containing protein 2
Gene Name Name: MARVELD2
Synonyms:TRIC;
Organism Homo sapiens (Human)

PRO ID PR:Q8N4S9
DAG View
PRO Name MARVEL domain-containing protein 2 (human)
Definition A MARVEL domain-containing protein 2 that is encoded in the genome of human.
Short Label hMARVELD2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N4S9 (MARVELD2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y14 Phosphorylation PhosphoSitePlus
Y23 Phosphorylation PhosphoSitePlus
T26 Phosphorylation PhosphoSitePlus
T27 Phosphorylation PhosphoSitePlus
S37 Phosphorylation PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
K101 Ubiquitination PhosphoSitePlus
S104 Phosphorylation PhosphoSitePlus
S116 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983
S120 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983
S128 Phosphorylation PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
Y137 Phosphorylation PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus
S146 Phosphorylation PhosphoSitePlus
K148 Ubiquitination PhosphoSitePlus
Y159 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
S161 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983
T166 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332, 23186163
T168 Phosphorylation PhosphoSitePlus
S173 Phosphorylation PhosphoSitePlus
K175 Ubiquitination PhosphoSitePlus
Y304 Phosphorylation PhosphoSitePlus
Y377 Phosphorylation PhosphoSitePlus
S387 Phosphorylation PhosphoSitePlus   UniProt 23186163
K391 Ubiquitination PhosphoSitePlus
S407 Phosphorylation PhosphoSitePlus
K412 Ubiquitination PhosphoSitePlus
Y442 Phosphorylation PhosphoSitePlus
Y446 Phosphorylation PhosphoSitePlus
S467 Phosphorylation PhosphoSitePlus
Y469 Phosphorylation PhosphoSitePlus
K548 Ubiquitination PhosphoSitePlus
Y557 Phosphorylation PhosphoSitePlus
S558 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K87 N87 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
S116 * Biomuta DOID:3571 / liver cancer [ tcga ]
S128 L128 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
S146 F146 Biomuta DOID:1909 / melanoma [ tcga ]
S558 Y558 Biomuta DOID:1909 / melanoma [ cosmic ]
S558 C558 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ]