Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N4P3 / MESH1_HUMAN
Protein Name Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1
Gene Name Name: HDDC3
Synonyms:MESH1;
Organism Homo sapiens (Human)

PRO ID PR:Q8N4P3
DAG View
PRO Name guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 (human)
Definition A guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 that is encoded in the genome of human.
Short Label hHDDC3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N4P3 (HDDC3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
G2 Acetylation UniProt 19413330
S3 Phosphorylation PhosphoSitePlus
K25 Acetylation PhosphoSitePlus   UniProt 19608861
T90 Phosphorylation PhosphoSitePlus
K93 Acetylation PhosphoSitePlus
K97 Acetylation PhosphoSitePlus   UniProt 19608861
K123 Acetylation PhosphoSitePlus   UniProt 19608861
K123 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T90 Phosphorylation HPRD 19664994


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K93 N93 Biomuta DOID:363 / uterine cancer [ tcga ]