iPTMnet Report for Q8N4N8 (KIF2B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N4N8 / KIF2B_HUMAN
Protein Name Kinesin-like protein KIF2B
Gene Name Name: KIF2B
Organism Homo sapiens (Human)

PRO ID PR:Q8N4N8
DAG View
PRO Name kinesin-like protein KIF2B (human)
Definition A kinesin-like protein KIF2B that is encoded in the genome of human.
Short Label hKIF2B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N4N8 (KIF2B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T111 Phosphorylation PhosphoSitePlus
T113 Phosphorylation PhosphoSitePlus
T125 Phosphorylation P53350 (PLK1) neXtProt   PhosphoSitePlus   RLIMS-P   Signor   UniProt 22535524
S127 Phosphorylation PhosphoSitePlus
S130 Phosphorylation PhosphoSitePlus
S137 Phosphorylation PhosphoSitePlus
S147 Phosphorylation PhosphoSitePlus   RLIMS-P 22535524
S200 Phosphorylation PhosphoSitePlus   RLIMS-P 22535524
S201 Phosphorylation PhosphoSitePlus   RLIMS-P 22535524
S204 Phosphorylation P53350 (PLK1) neXtProt   PhosphoSitePlus   RLIMS-P   Signor   UniProt 22535524
T344 Phosphorylation PhosphoSitePlus
Y360 Phosphorylation PhosphoSitePlus
K442 Ubiquitination PhosphoSitePlus
S444 Phosphorylation PhosphoSitePlus
T457 Phosphorylation PhosphoSitePlus
T458 Phosphorylation PhosphoSitePlus
S474 Phosphorylation PhosphoSitePlus
Y536 Phosphorylation HPRD   PhosphoSitePlus 20068231
K541 Methylation PhosphoSitePlus
K541 Ubiquitination PhosphoSitePlus
Y555 Phosphorylation PhosphoSitePlus
S567 Phosphorylation PhosphoSitePlus
S572 Phosphorylation PhosphoSitePlus
S575 Phosphorylation PhosphoSitePlus
T603 Phosphorylation PhosphoSitePlus
T609 Phosphorylation PhosphoSitePlus
T610 Phosphorylation PhosphoSitePlus
S616 Phosphorylation PhosphoSitePlus
S617 Phosphorylation PhosphoSitePlus
S643 Phosphorylation PhosphoSitePlus
K669 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T111 S111 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T113 M113 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:11934 / head and neck cancer [ icgc ] DOID:8618 / oral cavity cancer [ cosmic ]
S127 L127 Biomuta DOID:5041 / esophageal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S137 R137 Biomuta DOID:1612 / breast cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S200 R200 Biomuta DOID:184 / bone cancer [ cosmic ]
S201 R201 Biomuta DOID:5158 / pleural cancer [ cosmic ]
Y360 F360 Biomuta [ cosmic ]
S444 P444 Biomuta DOID:1115 / sarcoma [ icgc ]
S444 F444 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
T457 I457 Biomuta DOID:1324 / lung cancer [ cosmic ]
S474 C474 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K541 N541 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S567 C567 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S567 I567 Biomuta DOID:1324 / lung cancer [ cosmic ]
S572 L572 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S572 A572 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S616 C616 Biomuta DOID:263 / kidney cancer [ cosmic ]
S617 G617 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S643 P643 Biomuta DOID:363 / uterine cancer [ icgc ]
S643 F643 Biomuta DOID:4159 / skin cancer [ cosmic ]
K669 R669 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]