iPTMnet Report Q8N3Y7 SDR16C5

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q8N3Y7 / RDHE2_HUMAN
Protein Name	Epidermal retinol dehydrogenase 2
Gene Name	Name: SDR16C5 Synonyms:RDHE2;
Organism	Homo sapiens (Human)

PRO ID	PR:Q8N3Y7 DAG View
PRO Name	epidermal retinol dehydrogenase 2 (human)
Definition	An epidermal retinol dehydrogenase 2 that is encoded in the genome of human.
Short Label	hSDR16C5
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q8N3Y7 (SDR16C5) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S2	O-Glycosylation		score1	GlyGen	30379171, 30397120
	S7	O-Glycosylation		score1	GlyGen	30379171, 30397120
	S8	O-Glycosylation		score1	GlyGen	30379171, 30397120
	K102	Ubiquitination		score1	PhosphoSitePlus
	K114	Ubiquitination		score1	PhosphoSitePlus
	K132	Ubiquitination		score1	PhosphoSitePlus
	K133	Ubiquitination		score1	PhosphoSitePlus

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S2	Phosphorylation		score0	HPRD	20068231
	S21	Phosphorylation		score0	HPRD	20068231

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
S2	Y2	Biomuta		DOID:9256 / colorectal cancer [ icgc ]
K114	R114	Biomuta		DOID:4159 / skin cancer [ cosmic, icgc ]