iPTMnet Report for Q8N3Y3 (LARGE2)
Protein Information
| UniProt AC / UniProt ID | Q8N3Y3 / LARG2_HUMAN |
| Protein Name | Xylosyl- and glucuronyltransferase LARGE2 |
| Gene Name | Name: LARGE2 Synonyms:GYLTL1B;ORFNames:PP5656; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8N3Y3 |
| PRO Name | xylosyl- and glucuronyltransferase LARGE2 (human) |
| Definition | A xylosyl- and glucuronyltransferase LARGE2 that is encoded in the genome of human. |
| Short Label | hLARGE2 |
| Category | organism-gene |
DAG ViewQ8N3Y3 (LARGE2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| N80 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
| S679 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20166139 | ||
| T681 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20166139 | ||
| Y682 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20166139 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T681 | A681 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| Y682 | H682 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |
