iPTMnet Report for Q8N3V7 (SYNPO)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N3V7 / SYNPO_HUMAN
Protein Name Synaptopodin
Gene Name Name: SYNPO
Synonyms:KIAA1029;
Organism Homo sapiens (Human)

PRO ID PR:Q8N3V7
DAG View
PRO Name synaptopodin (human)
Definition A synaptopodin that is encoded in the genome of human.
Short Label hSYNPO
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N3V7 (SYNPO) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
T76 Phosphorylation PhosphoSitePlus
S122 Phosphorylation PhosphoSitePlus
S165 O-Glycosylation GlyGen 20068230
S235 Phosphorylation PhosphoSitePlus
S249 Phosphorylation PhosphoSitePlus
K260 Ubiquitination PhosphoSitePlus
S263 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231, ...24275569
S289 Phosphorylation PhosphoSitePlus
N330 N-Glycosylation GlyGen   UniProt 19159218
S405 O-Glycosylation GlyGen 30379171, 34725712, 30059200, ...35254053, 31492838, 30620550, 28657654, 29237092, 20068230
S405 Phosphorylation PhosphoSitePlus
T406 O-Glycosylation GlyGen 30379171, 34725712, 30059200, ...35254053, 31492838, 30620550, 28657654, 29237092, 20068230
T406 Phosphorylation PhosphoSitePlus
T409 O-Glycosylation GlyGen   PhosphoSitePlus 30379171, 34725712, 30059200, ...35254053, 31492838, 30620550, 28657654, 29237092, 20068230
T410 O-Glycosylation GlyGen 30379171, 34725712, 30059200, ...35254053, 31492838, 30620550, 28657654, 29237092, 20068230
T411 O-Glycosylation GlyGen 30379171, 34725712, 30059200, ...35254053, 31492838, 30620550, 28657654, 29237092, 20068230
S412 O-Glycosylation GlyGen 30379171, 34725712, 30059200, ...35254053, 31492838, 30620550, 28657654, 29237092, 20068230
T413 O-Glycosylation GlyGen 30379171, 34725712, 30059200, ...35254053, 31492838, 30620550, 28657654, 29237092, 20068230
S415 O-Glycosylation GlyGen 30379171, 34725712, 30059200, ...35254053, 31492838, 30620550, 28657654, 29237092, 20068230
S448 O-Glycosylation GlyGen 30379171, 34725712, 30059200, ...35254053, 31492838, 30620550, 28657654, 29237092, 20068230
T460 Phosphorylation PhosphoSitePlus
T463 Phosphorylation PhosphoSitePlus
Y466 Phosphorylation PhosphoSitePlus
S467 Phosphorylation PhosphoSitePlus
K475 Ubiquitination PhosphoSitePlus
S478 Phosphorylation PhosphoSitePlus
T495 Phosphorylation PhosphoSitePlus
S501 Phosphorylation PhosphoSitePlus
S525 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S534 Phosphorylation PhosphoSitePlus
S536 Phosphorylation PhosphoSitePlus
S548 Phosphorylation PhosphoSitePlus
S551 Phosphorylation PhosphoSitePlus
T560 O-Glycosylation GlyGen 30379171, 34725712, 30059200, ...35254053, 31492838, 30620550, 28657654, 29237092, 20068230
T564 O-Glycosylation GlyGen 30379171, 34725712, 30059200, ...35254053, 31492838, 30620550, 28657654, 29237092, 20068230
T566 O-Glycosylation GlyGen 30379171, 34725712, 30059200, ...35254053, 31492838, 30620550, 28657654, 29237092, 20068230
S570 O-Glycosylation GlyGen 30379171, 34725712, 30059200, ...35254053, 31492838, 30620550, 28657654, 29237092, 20068230
S580 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231, ...24275569
Y584 Phosphorylation phospho.ELM 18669648
S591 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K599 Ubiquitination PhosphoSitePlus
K607 Ubiquitination PhosphoSitePlus
S614 Phosphorylation PhosphoSitePlus
S623 Phosphorylation PhosphoSitePlus
K630 Ubiquitination PhosphoSitePlus
K632 Ubiquitination PhosphoSitePlus
K649 Ubiquitination PhosphoSitePlus
S685 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 18220336, ...18669648, 24275569, 20068231
S698 Phosphorylation PhosphoSitePlus
C699 Methylation IEDB 31844290
S702 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 18220336
S718 Phosphorylation PhosphoSitePlus
S721 Phosphorylation PhosphoSitePlus
K723 Ubiquitination PhosphoSitePlus
K737 Ubiquitination PhosphoSitePlus
Y738 Phosphorylation UniProt 24275569
S742 Phosphorylation PhosphoSitePlus
S744 Phosphorylation PhosphoSitePlus
T746 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S754 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 24275569
T756 Phosphorylation PhosphoSitePlus
S758 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S762 Phosphorylation PhosphoSitePlus
S777 Phosphorylation PhosphoSitePlus
S779 Phosphorylation PhosphoSitePlus
T783 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
P784 Phosphorylation UniProt 24275569
S787 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y789 Phosphorylation PhosphoSitePlus
T804 Phosphorylation UniProt 24275569
R812 Phosphorylation UniProt 24275569
S814 Phosphorylation PhosphoSitePlus
S819 Phosphorylation PhosphoSitePlus
K826 Phosphorylation UniProt 18669648, 24275569
S828 Phosphorylation PhosphoSitePlus
S833 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231, ...24275569
S838 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S839 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S854 Phosphorylation PhosphoSitePlus   UniProt 20068231, 24275569
S863 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S864 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y868 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S870 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
P871 Phosphorylation UniProt 17081983, 20068231, 18220336
S875 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S882 Phosphorylation PhosphoSitePlus
Y885 Phosphorylation PhosphoSitePlus
S890 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S893 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
P894 Phosphorylation UniProt 18669648, 24275569
S895 Phosphorylation PhosphoSitePlus
K903 Methylation PhosphoSitePlus
S909 Phosphorylation PhosphoSitePlus
S911 Phosphorylation PhosphoSitePlus
C927 Methylation IEDB 31844290
Site PTM Type PTM Enzyme Score Source PMID
S19 Phosphorylation HPRD 18669648, 20068231
Y222 Phosphorylation HPRD   PhosphoSitePlus 15592455
S281 Phosphorylation HPRD 18767875, 18669648, 17081983
S336 Phosphorylation HPRD 18669648, 20058876, 18212344, ...20068231, 19691289
Y340 Phosphorylation HPRD 18669648
S347 Phosphorylation HPRD 18669648
S351 Phosphorylation phospho.ELM 18669648
S376 Phosphorylation phospho.ELM 18669648
S441 Phosphorylation HPRD 20166139, 18669648, 17081983, ...20068231, 18452278
S458 Phosphorylation HPRD 18669648
S498 Phosphorylation HPRD 20068231
T502 Phosphorylation HPRD 18669648, 20068231
S510 Phosphorylation HPRD 18669648, 17081983, 20068231
S514 Phosphorylation HPRD 18669648, 17081983, 20068231
S535 Phosphorylation HPRD 17081983
T539 Phosphorylation HPRD 18669648
S543 Phosphorylation HPRD 18669648
Y545 Phosphorylation HPRD 17081983
Y548 Phosphorylation HPRD 17081983
T560 Phosphorylation HPRD 17081983
Y565 Phosphorylation HPRD 17081983
S570 Phosphorylation HPRD 17081983, 20068231
S575 Phosphorylation HPRD 20068231
S584 Phosphorylation HPRD 20068231
S589 Phosphorylation HPRD 18491316, 17081983, 18767875, ...18452278, 18669648, 20166139, 20068231
S594 Phosphorylation HPRD 18669648
S595 Phosphorylation HPRD 18669648
S619 Phosphorylation HPRD 18669648, 17081983
S620 Phosphorylation HPRD 18669648
Y624 Phosphorylation HPRD 18669648
T625 Phosphorylation HPRD 17081983
S626 Phosphorylation HPRD 18669648
S631 Phosphorylation HPRD 18669648, 17081983
S646 Phosphorylation HPRD 18669648
S649 Phosphorylation HPRD 18669648
S681 Phosphorylation HPRD 17081983
T684 Phosphorylation HPRD 17081983, 20068231
S685 Phosphorylation HPRD 17081983, 20068231
T689 Phosphorylation HPRD   PhosphoSitePlus 17081983
S693 Phosphorylation HPRD   PhosphoSitePlus 17081983
S697 Phosphorylation HPRD 20068231
S704 Phosphorylation HPRD 20068231
S715 Phosphorylation PhosphoSitePlus
S718 Phosphorylation HPRD   PhosphoSitePlus 20068231
S729 Phosphorylation HPRD   PhosphoSitePlus 20068231
S736 Phosphorylation PhosphoSitePlus
S738 Phosphorylation HPRD   PhosphoSitePlus 17081983
S774 Phosphorylation HPRD   PhosphoSitePlus 18669648, 17081983
S784 Phosphorylation HPRD   PhosphoSitePlus 18669648, 17081983
S804 Phosphorylation HPRD   PhosphoSitePlus 20166139, 18669648, 20068231
S812 Phosphorylation HPRD   PhosphoSitePlus 17081983
S826 Phosphorylation HPRD   PhosphoSitePlus 18669648
S833 Phosphorylation PhosphoSitePlus
S834 Phosphorylation PhosphoSitePlus
T836 Phosphorylation HPRD   PhosphoSitePlus 18669648
S837 Phosphorylation PhosphoSitePlus
S840 Phosphorylation HPRD   PhosphoSitePlus 18669648, 17081983
S854 Phosphorylation HPRD   PhosphoSitePlus 17081983, 20068231, 19691289
T856 Phosphorylation HPRD   PhosphoSitePlus 18669648, 20068231, 18452278
S858 Phosphorylation HPRD   PhosphoSitePlus 17081983, 20068231
S861 Phosphorylation PhosphoSitePlus
S864 Phosphorylation PhosphoSitePlus
S867 Phosphorylation PhosphoSitePlus
S871 Phosphorylation HPRD   PhosphoSitePlus 17081983, 20068231, 18212344
S887 Phosphorylation PhosphoSitePlus
S894 Phosphorylation HPRD   PhosphoSitePlus 18669648, 18212344
S900 Phosphorylation PhosphoSitePlus
T903 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S19 Phosphorylation HPRD 18669648, 20068231
S281 Phosphorylation HPRD 18767875, 18669648
S336 Phosphorylation HPRD 18669648, 20058876, 18212344, ...20068231, 19691289
Y340 Phosphorylation HPRD 18669648
S347 Phosphorylation HPRD 18669648
S441 Phosphorylation HPRD 20166139, 18669648, 20068231, ...18452278
S458 Phosphorylation HPRD 18669648
S498 Phosphorylation HPRD 20068231
T502 Phosphorylation HPRD 18669648, 20068231
S510 Phosphorylation HPRD 18669648, 20068231
S514 Phosphorylation HPRD 18669648, 20068231
T539 Phosphorylation HPRD 18669648
S543 Phosphorylation HPRD 18669648
S570 Phosphorylation HPRD 20068231
S575 Phosphorylation HPRD 20068231
S584 Phosphorylation HPRD 20068231
S589 Phosphorylation HPRD 18491316, 18767875, 18452278, ...18669648, 20166139, 20068231
S594 Phosphorylation HPRD 18669648
S595 Phosphorylation HPRD 18669648
S619 Phosphorylation HPRD 18669648
S620 Phosphorylation HPRD 18669648
Y624 Phosphorylation HPRD 18669648
S626 Phosphorylation HPRD 18669648
S631 Phosphorylation HPRD 18669648
S646 Phosphorylation HPRD 18669648
S649 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S235 N235 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
S289 P289 Biomuta DOID:363 / uterine cancer [ icgc ]
S336 F336 Biomuta DOID:363 / uterine cancer [ icgc ]
S415 F415 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T460 I460 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S498 F498 Biomuta DOID:263 / kidney cancer [ cosmic ]
S501 N501 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S510 L510 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S514 F514 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S536 N536 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T539 P539 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S548 N548 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:2531 / hematologic cancer [ cosmic ]
S551 P551 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S580 F580 Biomuta DOID:363 / uterine cancer [ icgc ]
S619 Y619 Biomuta DOID:3571 / liver cancer [ cosmic ]
S623 F623 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S626 F626 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:10283 / prostate cancer [ cosmic ]
S646 P646 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S742 F742 Biomuta DOID:263 / kidney cancer [ cosmic ]
S744 N744 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S754 L754 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S758 F758 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S762 F762 Biomuta DOID:4159 / skin cancer [ cosmic ]
S774 L774 Biomuta DOID:1612 / breast cancer [ cosmic ]
T783 P783 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S784 P784 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S804 P804 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R812 C812 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
S837 T837 Biomuta DOID:263 / kidney cancer [ cosmic ]
S840 N840 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S858 C858 Biomuta DOID:10283 / prostate cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic, icgc, cosmic, icgc ] DOID:4362 / cervical cancer [ cosmic, icgc, cosmic, icgc ] DOID:263 / kidney cancer [ cosmic, icgc, cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S863 Y863 Biomuta DOID:3571 / liver cancer [ cosmic ]
S870 F870 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:10283 / prostate cancer [ cosmic ]
S890 P890 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S895 Y895 Biomuta DOID:4159 / skin cancer [ cosmic ]
K903 R903 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S909 F909 Biomuta DOID:4159 / skin cancer [ cosmic ]