iPTMnet Report Q8N3C0 ASCC3

Protein Information

UniProt AC / UniProt ID	Q8N3C0 / ASCC3_HUMAN
Protein Name	Activating signal cointegrator 1 complex subunit 3
Gene Name	Name: ASCC3 Synonyms:HELIC1,RQT2;
Organism	Homo sapiens (Human)

PRO ID	PR:Q8N3C0 DAG View
PRO Name	activating signal cointegrator 1 complex subunit 3 (human)
Definition	An activating signal cointegrator 1 complex subunit 3 that is encoded in the genome of human.
Short Label	hASCC3
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q8N3C0 (ASCC3) as Substrate

Expanded View

Search:

Site Select all By amino acid All Serine All Threonine All Tyrosine By position S12 K18 K30 K52 K57 K62 K78 K116 K155 R160 S170 K190 S193 K197 K198 T209 K213 S221 C225 T234 K236 S298 K311 K312 K319 K334 K338 K353 C366 K370 S385 K399 K414 K423 K436 S452 K456 K472 K527 K540 T565 K572 T578 T584 K587 T592 K594 S595 T631 S637 S640 K693 K710 K740 K761 K834 K860 K938 T973 Y975 K1006 K1017 K1025 T1104 T1106 Y1107 S1131 K1150 K1156 T1256 C1343 K1369 K1374 K1382 K1399 K1403 K1416 K1420 K1430 T1480 K1482 S1490 T1491 S1540 K1543 S1551 S1553 S1563 S1606 K1609 T1611 K1671 K1700 K1709 K1715 T1745 S1746 K1825 K1830 K1837 K1873 Y1909 T1915 K1976 K1983 K2022 K2065 K2070 K2097 K2111 S2195	PTM Type Select all Acetylation Methylation Phosphorylation Sumoylation Ubiquitination	Score Select all 1 2	Source Select all IEDB PhosphoSitePlus UniProt	PMID
S12	Phosphorylation	score2	PhosphoSitePlus UniProt	23186163
K18	Ubiquitination	score1	PhosphoSitePlus
K30	Ubiquitination	score1	PhosphoSitePlus
K52	Ubiquitination	score1	PhosphoSitePlus
K57	Ubiquitination	score1	PhosphoSitePlus
K62	Ubiquitination	score1	PhosphoSitePlus
K78	Ubiquitination	score1	PhosphoSitePlus
K116	Ubiquitination	score1	PhosphoSitePlus
K155	Ubiquitination	score1	PhosphoSitePlus
R160	Methylation	score1	PhosphoSitePlus
S170	Phosphorylation	score1	PhosphoSitePlus
K190	Ubiquitination	score1	PhosphoSitePlus
S193	Phosphorylation	score1	PhosphoSitePlus
K197	Ubiquitination	score1	PhosphoSitePlus
K198	Ubiquitination	score1	PhosphoSitePlus
T209	Phosphorylation	score1	PhosphoSitePlus
K213	Ubiquitination	score1	PhosphoSitePlus
S221	Phosphorylation	score1	PhosphoSitePlus
C225	Methylation	score1	IEDB	31844290
T234	Phosphorylation	score1	PhosphoSitePlus
K236	Ubiquitination	score1	PhosphoSitePlus
S298	Phosphorylation	score1	PhosphoSitePlus
K311	Ubiquitination	score1	PhosphoSitePlus
K312	Ubiquitination	score1	PhosphoSitePlus
K319	Ubiquitination	score1	PhosphoSitePlus
K334	Ubiquitination	score1	PhosphoSitePlus
K338	Ubiquitination	score1	PhosphoSitePlus
K353	Acetylation	score1	PhosphoSitePlus
C366	Methylation	score1	IEDB	31844290
K370	Ubiquitination	score1	PhosphoSitePlus
S385	Phosphorylation	score1	PhosphoSitePlus
K399	Ubiquitination	score1	PhosphoSitePlus
K414	Ubiquitination	score1	PhosphoSitePlus
K423	Ubiquitination	score1	PhosphoSitePlus
K436	Ubiquitination	score1	PhosphoSitePlus
S452	Phosphorylation	score1	PhosphoSitePlus
K456	Ubiquitination	score1	PhosphoSitePlus
K472	Ubiquitination	score1	PhosphoSitePlus
K527	Ubiquitination	score1	PhosphoSitePlus
K540	Ubiquitination	score1	PhosphoSitePlus
T565	Phosphorylation	score1	PhosphoSitePlus
K572	Acetylation	score2	PhosphoSitePlus UniProt	19608861
K572	Ubiquitination	score1	PhosphoSitePlus
T578	Phosphorylation	score1	PhosphoSitePlus
T584	Phosphorylation	score1	PhosphoSitePlus
K587	Ubiquitination	score1	PhosphoSitePlus
T592	Phosphorylation	score1	PhosphoSitePlus
K594	Ubiquitination	score1	PhosphoSitePlus
S595	Phosphorylation	score1	PhosphoSitePlus
T631	Phosphorylation	score1	IEDB	29493099
S637	Phosphorylation	score1	PhosphoSitePlus
S640	Phosphorylation	score1	PhosphoSitePlus
K693	Ubiquitination	score1	PhosphoSitePlus
K710	Ubiquitination	score1	PhosphoSitePlus
K740	Ubiquitination	score1	PhosphoSitePlus
K761	Ubiquitination	score1	PhosphoSitePlus
K834	Ubiquitination	score1	PhosphoSitePlus
K860	Ubiquitination	score1	PhosphoSitePlus
K938	Ubiquitination	score1	PhosphoSitePlus
T973	Phosphorylation	score1	PhosphoSitePlus
Y975	Phosphorylation	score1	PhosphoSitePlus
K1006	Ubiquitination	score1	PhosphoSitePlus
K1017	Ubiquitination	score1	PhosphoSitePlus
K1025	Ubiquitination	score1	PhosphoSitePlus
T1104	Phosphorylation	score1	PhosphoSitePlus
T1106	Phosphorylation	score1	PhosphoSitePlus
Y1107	Phosphorylation	score1	PhosphoSitePlus
S1131	Phosphorylation	score1	PhosphoSitePlus
K1150	Ubiquitination	score1	PhosphoSitePlus
K1156	Ubiquitination	score1	PhosphoSitePlus
T1256	Phosphorylation	score1	IEDB	32387766
C1343	Methylation	score1	IEDB	31844290
K1369	Ubiquitination	score1	PhosphoSitePlus
K1374	Ubiquitination	score1	PhosphoSitePlus
K1382	Methylation	score1	PhosphoSitePlus
K1382	Ubiquitination	score1	PhosphoSitePlus
K1399	Acetylation	score1	PhosphoSitePlus
K1399	Ubiquitination	score1	PhosphoSitePlus
K1403	Acetylation	score1	PhosphoSitePlus
K1403	Ubiquitination	score1	PhosphoSitePlus
K1416	Ubiquitination	score1	PhosphoSitePlus
K1420	Ubiquitination	score1	PhosphoSitePlus
K1430	Ubiquitination	score1	PhosphoSitePlus
T1480	Phosphorylation	score1	PhosphoSitePlus
K1482	Ubiquitination	score1	PhosphoSitePlus
S1490	Phosphorylation	score1	PhosphoSitePlus
T1491	Phosphorylation	score1	PhosphoSitePlus
S1540	Phosphorylation	score1	PhosphoSitePlus
K1543	Ubiquitination	score1	PhosphoSitePlus
S1551	Phosphorylation	score1	PhosphoSitePlus
S1553	Phosphorylation	score1	PhosphoSitePlus
S1563	Phosphorylation	score1	PhosphoSitePlus
S1606	Phosphorylation	score1	PhosphoSitePlus
K1609	Methylation	score1	PhosphoSitePlus
T1611	Phosphorylation	score1	PhosphoSitePlus
K1671	Ubiquitination	score1	PhosphoSitePlus
K1700	Ubiquitination	score1	PhosphoSitePlus
K1709	Acetylation	score1	PhosphoSitePlus
K1709	Ubiquitination	score1	PhosphoSitePlus
K1715	Sumoylation	score1	PhosphoSitePlus
T1745	Phosphorylation	score1	PhosphoSitePlus
S1746	Phosphorylation	score1	PhosphoSitePlus
K1825	Methylation	score1	PhosphoSitePlus
K1830	Ubiquitination	score1	PhosphoSitePlus
K1837	Ubiquitination	score1	PhosphoSitePlus
K1873	Ubiquitination	score1	PhosphoSitePlus
Y1909	Phosphorylation	score1	PhosphoSitePlus
T1915	Phosphorylation	score1	PhosphoSitePlus
K1976	Ubiquitination	score1	PhosphoSitePlus
K1983	Ubiquitination	score1	PhosphoSitePlus
K2022	Ubiquitination	score1	PhosphoSitePlus
K2065	Ubiquitination	score1	PhosphoSitePlus
K2070	Ubiquitination	score1	PhosphoSitePlus
K2097	Ubiquitination	score1	PhosphoSitePlus
K2111	Ubiquitination	score1	PhosphoSitePlus
S2195	Phosphorylation	score2	PhosphoSitePlus UniProt	23186163

Search:

Site Select all By amino acid All Serine All Threonine By position T565 S595 S1551 S1553 S1563 T1915 S2195	PTM Type Select all Phosphorylation	Score Select all 0	Source Select all HPRD	PMID
T565	Phosphorylation	score0	HPRD	19651622
S595	Phosphorylation	score0	HPRD	20068231
S1551	Phosphorylation	score0	HPRD	20068231
S1553	Phosphorylation	score0	HPRD	20068231
S1563	Phosphorylation	score0	HPRD	20068231
T1915	Phosphorylation	score0	HPRD	20068231
S2195	Phosphorylation	score0	HPRD	19664994

PTM sites affected in variants

Search:

Site Select all By amino acid All Serine All Threonine All Tyrosine By position S12 K30 K52 R160 S170 S221 T234 S298 K312 K572 T584 S640 K860 T1104 K1369 K1416 T1480 S1540 K1609 T1611 K1671 Y1909 K1983 K2097 S2195	Variant Select all * A1480 A1611 A234 C1909 E1369 E1609 F12 F221 I1104 I1416 I1611 I640 I860 L170 M160 N1540 N2097 N30 N312 N52 P584 R1671 R1983 T2195 T312 T572	Source Select all Biomuta	Disease [Sample source] Select all DOID:10534 / stomach cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:1612 / breast cancer [ icgc ] DOID:1793 / pancreatic cancer [ icgc ] DOID:3571 / liver cancer [ cosmic, icgc ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic, icgc ] DOID:4606 / bile duct cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ] [ cosmic ]
S12	F12	Biomuta	DOID:4159 / skin cancer [ cosmic ]
K30	N30	Biomuta	DOID:4159 / skin cancer [ cosmic, icgc ]
K52	N52	Biomuta	DOID:9256 / colorectal cancer [ cosmic ]
R160	M160	Biomuta	DOID:1319 / brain cancer [ cosmic ]
S170	L170	Biomuta	DOID:4159 / skin cancer [ cosmic ]
S170	*	Biomuta	DOID:11054 / urinary bladder cancer [ cosmic ]
S221	F221	Biomuta	DOID:4159 / skin cancer [ cosmic ]
T234	A234	Biomuta	DOID:1324 / lung cancer [ cosmic ]
S298	*	Biomuta	DOID:11054 / urinary bladder cancer [ cosmic ]
K312	T312	Biomuta	DOID:10534 / stomach cancer [ cosmic, icgc ]
K312	N312	Biomuta	DOID:363 / uterine cancer [ cosmic, icgc ]
K572	T572	Biomuta	DOID:9256 / colorectal cancer [ cosmic ]
T584	P584	Biomuta	DOID:3571 / liver cancer [ cosmic, icgc ]
S640	I640	Biomuta	DOID:4606 / bile duct cancer [ cosmic ]
K860	I860	Biomuta	DOID:1324 / lung cancer [ cosmic ]
T1104	I1104	Biomuta	DOID:9256 / colorectal cancer [ cosmic ]
K1369	E1369	Biomuta	DOID:363 / uterine cancer [ icgc ]
K1416	I1416	Biomuta	DOID:9256 / colorectal cancer [ cosmic, icgc ]
T1480	A1480	Biomuta	DOID:1793 / pancreatic cancer [ icgc ]
S1540	N1540	Biomuta	DOID:9256 / colorectal cancer [ cosmic, icgc ]
K1609	E1609	Biomuta	DOID:1612 / breast cancer [ icgc ]
T1611	A1611	Biomuta	DOID:10534 / stomach cancer [ cosmic, icgc ]
T1611	I1611	Biomuta	[ cosmic ]
K1671	R1671	Biomuta	DOID:10534 / stomach cancer [ cosmic ]
Y1909	C1909	Biomuta	DOID:5041 / esophageal cancer [ cosmic ]
K1983	R1983	Biomuta	DOID:5041 / esophageal cancer [ cosmic ]
K2097	N2097	Biomuta	DOID:5041 / esophageal cancer [ cosmic ]
S2195	T2195	Biomuta	DOID:4159 / skin cancer [ cosmic ]

PTM Type		Select All, None
Acetylation	N-Glycosylation	O-Glycosylation
C-Glycosylation	S-Glycosylation	Methylation
Myristoylation	Phosphorylation	Sumoylation
Ubiquitination	S-Nitrosylation

Select organisms		Select All, None
Human	Mouse	Rat
Cow	Chicken	Zebrafish
Fruit fly	C. elegans	Baker's yeast
Fission yeast	A. thaliana	Maize
M. truncatula	Rice (japonica)	Rice (indica)

Or input other organisms

iPTMnet Report for Q8N3C0 (ASCC3)

Protein Information

Interactive Sequence View

Q8N3C0 (ASCC3) as Substrate

PTM sites affected in variants