iPTMnet Report for Q8N370 (SLC43A2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N370 / LAT4_HUMAN
Protein Name Large neutral amino acids transporter small subunit 4
Gene Name Name: SLC43A2
Synonyms:LAT4;ORFNames:PP7664;
Organism Homo sapiens (Human)

PRO ID PR:Q8N370
DAG View
PRO Name large neutral amino acids transporter small subunit 4 (human)
Definition A large neutral amino acids transporter small subunit 4 that is encoded in the genome of human.
Short Label hSLC43A2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N370 (SLC43A2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S249 Phosphorylation PhosphoSitePlus
K260 Ubiquitination PhosphoSitePlus
T267 Phosphorylation PhosphoSitePlus
S274 Phosphorylation IEDB   PhosphoSitePlus   UniProt 30379325, 35494241, 18669648
S277 Phosphorylation PhosphoSitePlus
S278 Phosphorylation PhosphoSitePlus   UniProt 18669648
K283 Ubiquitination PhosphoSitePlus
K293 Ubiquitination PhosphoSitePlus
S297 Phosphorylation PhosphoSitePlus   UniProt 30379325, 23186163
T298 Phosphorylation PhosphoSitePlus
K402 Ubiquitination PhosphoSitePlus
K558 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S274 Phosphorylation HPRD 18669648
S278 Phosphorylation HPRD 18669648
S297 Phosphorylation HPRD 18669648, 19664995


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S249 I249 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S249 R249 Biomuta DOID:1612 / breast cancer [ icgc ]
S249 N249 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
S274 I274 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
T298 S298 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]